Long L L, Peng P, Huang Z K
Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Zhonghua Gan Zang Bing Za Zhi. 2017 May 20;25(5):329-332. doi: 10.3760/cma.j.issn.1007-3418.2017.05.003.
Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver, and in the process of HCC development, early identification and timely treatment can significantly improve patient survival rate. Imaging techniques play an important role in the monitoring of chronic liver diseases, evolution of cirrhotic nodules, and early diagnosis of HCC. Multi-phase or dynamic contrast-enhanced computed tomography and magnetic resonance imaging (MRI) reflect the changes in blood supply during the evolution of liver cirrhotic nodules. Functional MRI can reflect the structure and function of living organisms at the molecular level. The application of liver-specific contrast agents can improve the detection rate and identification of early-stage HCC. With the development of MRI techniques and the accumulation of clinical experience in functional imaging will further improve the diagnostic rate of early-stage HCC.
肝细胞癌(HCC)是肝脏最常见的原发性恶性肿瘤,在HCC发展过程中,早期识别和及时治疗可显著提高患者生存率。成像技术在慢性肝病监测、肝硬化结节演变及HCC早期诊断中发挥着重要作用。多期或动态对比增强计算机断层扫描和磁共振成像(MRI)反映肝硬化结节演变过程中的血供变化。功能MRI可在分子水平反映生物体的结构和功能。肝脏特异性对比剂的应用可提高早期HCC的检出率和鉴别能力。随着MRI技术的发展以及功能成像临床经验的积累,将进一步提高早期HCC的诊断率。