Nelson W L, Hopkins R S, Roe M H, Glode M P
Pediatr Infect Dis. 1986 Sep-Oct;5(5):540-4. doi: 10.1097/00006454-198609000-00010.
We compared three groups of hospitalized children with Bordetella pertussis infection, respiratory syncytial virus (RSV) infection and dual B. pertussis/RSV infections in an effort to establish clinical and laboratory criteria by which to distinguish children with dual infections from children infected with either organism alone. The groups were compared for admission laboratory data, history of present illness, perinatal history and immunization history. Children with pertussis were more likely to have been premature (less than 37 weeks gestation) than children with RSV infections only (11 of 29 vs. 1 of 22, chi square test, 5.94, P less than 0.02). Other than B. pertussis and RSV fluorescent antibody testing and culture, there were no laboratory or clinical criteria by which to differentiate these children consistently at the time of hospital admission. For purposes of medical management and infection control, pertussis or simultaneous infection with pertussis should be considered in young children hospitalized for presumed viral respiratory illness.
我们比较了三组住院儿童，分别为感染百日咳博德特氏菌、呼吸道合胞病毒（RSV）以及同时感染百日咳博德特氏菌/RSV的儿童，旨在建立临床和实验室标准，以便区分同时感染的儿童与仅感染单一病原体的儿童。对这几组儿童的入院实验室数据、现病史、围产期病史和免疫史进行了比较。与仅感染RSV的儿童相比，患百日咳的儿童更有可能早产（妊娠少于37周）（29例中有11例，22例中有1例，卡方检验，5.94，P<0.02）。除了百日咳博德特氏菌和RSV荧光抗体检测及培养外，在入院时没有实验室或临床标准能始终如一地区分这些儿童。出于医疗管理和感染控制的目的，对于因疑似病毒性呼吸道疾病住院的幼儿，应考虑百日咳或百日咳合并感染。
