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脐带血中的铅含量及其对新生儿人体测量学的影响。

Lead Level in Umbilical Cord Blood and its Effects on Newborns Anthropometry.

作者信息

Neda Akbari-Nassaji, Fahimeh Sabeti, Tahereh Ziaei Kajbaf, Leila Fakharzadeh, Zahra Nazari, Bahman Cheraghian, Narges Cham Kouri

机构信息

MS, Department of Nursing, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Abadan School of Medical Sciences, Abadan, Iran.

MS, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Department of Pediatric Nursing, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.

出版信息

J Clin Diagn Res. 2017 Jun;11(6):SC01-SC04. doi: 10.7860/JCDR/2017/24865.10016. Epub 2017 Jun 1.

Abstract

INTRODUCTION

High concentration of blood lead is accompanied by adverse health effects on growth of foetus and the newborn.

AIM

The aim of this study was to determine umbilical cord blood lead level and its relationship with birth weight, length and head circumference of the newborns in Abadan, Iran.

MATERIALS AND METHODS

In this cross-sectional study, 3 ml blood was collected from the umbilical cord vein in 147 newborns, immediately after the birth. Blood lead was measured using atomic absorption spectrophotometry. Data collection instruments included demographic questionnaire (age of mother, gestational age, newborn gender, job and education of mother) and also data registration form (umbilical cord blood lead concentration, weight, length, and head circumference of newborn). Data was analyzed with SPSS software version 16.0.

RESULTS

The mean of umbilical cord blood lead was determined 0.65±0.32 µg/dl (0.3-1.35 µg/dl). The decrease of birth weight with increased blood lead level was small and was not statistically significant. There was reverse significant correlation between umbilical cord blood lead level and birth length and head circumference. There was no significant correlation between blood lead and other variables such as age, weight, education and job of mother and gestational age.

CONCLUSION

Umbilical blood lead level was determined <5 µg/ dl. Excess of umbilical cord blood lead caused decreasing birth weight, length and head circumference of the newborns.

摘要

引言

高血铅水平会对胎儿和新生儿的生长产生不良健康影响。

目的

本研究的目的是确定伊朗阿巴丹新生儿的脐带血铅水平及其与出生体重、身长和头围的关系。

材料与方法

在这项横断面研究中,147名新生儿出生后立即从脐静脉采集3毫升血液。使用原子吸收分光光度法测量血铅。数据收集工具包括人口统计学问卷(母亲年龄、孕周、新生儿性别、母亲职业和教育程度)以及数据登记表(脐带血铅浓度、新生儿体重、身长和头围)。数据用SPSS 16.0软件进行分析。

结果

脐带血铅平均值确定为0.65±0.32微克/分升(0.3 - 1.35微克/分升)。出生体重随血铅水平升高而降低的幅度较小,且无统计学意义。脐带血铅水平与出生身长和头围呈显著负相关。血铅与母亲年龄、体重、教育程度、职业以及孕周等其他变量之间无显著相关性。

结论

脐带血铅水平确定<5微克/分升。脐带血铅超标导致新生儿出生体重、身长和头围降低。

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