Abdi Fatemeh, Roozbeh Nasibeh, Mortazavian Amir Mohammad
Student Research Committee, Nursing and Midwifery Faculty, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mother and Child Welfare Research Center, Hormozgan Universiy of Medical Sciences, BandarAbbas, Iran.
BMC Res Notes. 2017 Aug 1;10(1):363. doi: 10.1186/s13104-017-2697-3.
Over 10-15% of couples in different countries are infertile. Male infertility is a contributing factor and the only cause of infertility in respectively 50% and 20-30% of all cases of infertility. According to previous research, micro-elements isolated from date palm pollen (DPP), e.g. estrogen and sterols, may enhance male and female fertility. DPP has also been reported to improve sperm parameters including sperm motility and viability, acrosome reaction, and lipid peroxidation. This article may justify the need for a future systematic review and meta-analysis about the effects of DPP on the reproductive system and DPP's ability to enhance fertility. It will then describe the methodology of such a study.
A comprehensive search of relevant randomized and quasi-randomized controlled trials will be performed in MEDLINE, EMBASE, Web of Science, Cochrane Central, ProQuest, and Google Scholar databases. Two authors will independently assess the eligibility of the studies and consult the third author in cases of disagreement. The risk of bias of the randomized controlled trials and animal studies will be evaluated using the Cochrane risk of bias tool and the Systematic Review Centre for Laboratory animal Experimentation (SYRCLE) risk of bias tool, respectively. This study will raise no ethical issues as it will review the findings of previous research. The results are intended to be published in a peer-reviewed medical journal.
不同国家超过10% - 15%的夫妇患有不孕症。男性不育是一个促成因素，在所有不孕症病例中分别占50%以及20% - 30%的唯一病因。根据先前的研究，从椰枣花粉（DPP）中分离出的微量元素，如雌激素和甾醇，可能会提高男性和女性的生育能力。据报道，DPP还能改善精子参数，包括精子活力和存活率、顶体反应以及脂质过氧化。本文可能证明有必要对DPP对生殖系统的影响及其提高生育能力的能力进行未来的系统评价和荟萃分析。然后将描述此类研究的方法。
将在MEDLINE、EMBASE、科学网、Cochrane中心、ProQuest和谷歌学术数据库中对相关随机和半随机对照试验进行全面检索。两位作者将独立评估研究的 eligibility，并在意见不一致的情况下咨询第三位作者。将分别使用Cochrane偏倚风险工具和实验动物系统评价中心（SYRCLE）偏倚风险工具评估随机对照试验和动物研究的偏倚风险。由于本研究将回顾先前研究的结果，因此不会引发伦理问题。结果拟发表在同行评审的医学杂志上。
