Oldroyd Alexander, Lilleker James, Chinoy Hector
Centre for Musculoskeletal Research, University of Manchester, Manchester, UK and NIHR Manchester Biomedical Research Centre, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK
NIHR Manchester Biomedical Research Centre, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK and Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.
Clin Med (Lond). 2017 Jul;17(4):322-328. doi: 10.7861/clinmedicine.17-4-322.
The idiopathic inflammatory myopathies are a group of conditions characterised by inflammation of muscles (myositis) and other body systems. The diagnosis can be challenging because of the many potential clinical features and extra-muscular manifestations, which may be seemingly unrelated. An accurate diagnosis requires up-to-date understanding of the clinical manifestations, different clinical subtypes and appropriate interpretation of investigations, including newly described serological subtypes.This review will detail the approach to the diagnosis of an idiopathic inflammatory myopathy, based on up-to-date knowledge. The recently updated classification criteria and treatment options will also be described.
特发性炎性肌病是一组以肌肉炎症(肌炎)和其他身体系统炎症为特征的疾病。由于存在许多潜在的临床特征和肌肉外表现,且这些表现可能看似无关,因此诊断具有挑战性。准确的诊断需要对临床表现、不同临床亚型有最新的了解,并对包括新描述的血清学亚型在内的检查结果进行恰当解读。本综述将根据最新知识详细阐述特发性炎性肌病的诊断方法。还将介绍最近更新的分类标准和治疗选择。