Al Sharji Marwa, Al Busaidi Salim, Al Jahdhami Suad, Jawa Zabah, Farhan Hatem, Al Alawi Abdullah M
Internal Medicine Residency Program, Oman Medical Specialty Board, Muscat, Oman.
Department of Medicine, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman.
Sultan Qaboos Univ Med J. 2024 Nov;24(4):593-598. doi: 10.18295/squmj.6.2024.039. Epub 2024 Nov 27.
Inclusion body myositis (IBM) is a rare progressive myopathy affecting individuals older than 50 years. It is associated with significant morbidity by restricting the patient's mobility and it has a relatively low mortality risk with respiratory muscles involvement. Muscle biopsy is the gold standard method for diagnosis. We report a 72-year-old female patient who was admitted to a tertiary care hospital in Muscat, Oman, in 2023 with progressive weakness of lower limbs. Various diagnostic tests were performed and the patient was subsequently diagnosed with IBM. The patient was treated with methylprednisolone, immunoglobulins, rituximab and prednisolone; this resulted in moderate clinical improvement. This case highlights the intricate nature of the diagnostic journey, as diagnosing IBM remains a challenge in clinical practice, requiring a high degree of suspicion and precise application of available diagnostic tools with the guidance of a collaborative multidisciplinary approach in investigating and providing patient care. This case report contributes valuable insights to the understanding of this complex myopathy, facilitating more accurate diagnosis and enhancing patient care strategies.
包涵体肌炎（IBM）是一种罕见的进行性肌病，影响50岁以上的个体。它通过限制患者的活动能力而导致显著的发病率，并且在呼吸肌受累的情况下具有相对较低的死亡风险。肌肉活检是诊断的金标准方法。我们报告了一名72岁的女性患者，她于2023年入住阿曼马斯喀特的一家三级护理医院，下肢进行性无力。进行了各种诊断测试，患者随后被诊断为IBM。该患者接受了甲基强的松龙、免疫球蛋白、利妥昔单抗和强的松龙治疗；这导致了中度的临床改善。该病例突出了诊断过程的复杂性，因为在临床实践中诊断IBM仍然是一项挑战，需要高度的怀疑，并在协作多学科方法的指导下精确应用可用的诊断工具来调查和提供患者护理。本病例报告为理解这种复杂的肌病提供了有价值的见解，有助于更准确的诊断并加强患者护理策略。
