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复杂的自行推进环:细胞运动的最简模型。

Complex self-propelled rings: a minimal model for cell motility.

机构信息

Theoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, 52425 Jülich, Germany.

出版信息

Soft Matter. 2017 Sep 13;13(35):5865-5876. doi: 10.1039/c7sm00439g.

DOI:10.1039/c7sm00439g
PMID:28766641
Abstract

Collective behavior of active matter is observed for self-propelled particles, such as vibrated disks and active Brownian particles, as well as for cytoskeletal filaments in motile cells. Here, a system of quasi two-dimensional penetrable self-propelled rods inside rigid rings is used to construct a complex self-propelled particle. The rods interact sterically with each other and with a stationary or mobile ring via a separation-shifted Lennard-Jones potential. They either have a sliding attachment to the inside of the ring at one of their ends, or can move freely within the ring confinement. We study the inner structure and dynamics of the mobile self-propelled rings. We find that these complex particles cannot only be characterized as active Brownian particles, but can also exhibit cell-like motility: random walks, persistent motion, circling, and run-and-circle motion.

摘要

活性物质的集体行为在自推进粒子中得到了观察,例如振动圆盘和活性布朗粒子,以及在运动细胞中的细胞骨架丝。在这里,使用准二维可穿透的自推进杆在刚性环内构建了一个复杂的自推进粒子系统。这些杆通过分离位移 Lennard-Jones 势与彼此以及与静止或移动的环相互作用。它们的一端要么在环的内部有滑动连接,要么可以在环的限制内自由移动。我们研究了移动自推进环的内部结构和动力学。我们发现,这些复杂的粒子不仅可以被描述为活性布朗粒子,还可以表现出类似细胞的运动方式:随机行走、持续运动、盘旋和跑圈运动。

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Complex self-propelled rings: a minimal model for cell motility.复杂的自行推进环:细胞运动的最简模型。
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