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Polymorphic restriction sites in the horse beta-globin gene cluster.

作者信息

Rando A, Di Gregorio P, Masina P

出版信息

Anim Genet. 1986;17(3):245-53. doi: 10.1111/j.1365-2052.1986.tb03196.x.

DOI:10.1111/j.1365-2052.1986.tb03196.x
PMID:2876665
Abstract

Horse DNA samples digested with PstI and probed with the rabbit beta 1 globin gene show three phenotypes determined by one fragment of variable length (about 5.1 or 3.3 kb). Family data demonstrate that these fragments segregate as Mendelian alleles. The frequencies of the two alleles are 0.66 for the 3.3-kb fragment and 0.34 for the 5.1-kb one. Another polymorphism has been detected with BamHI. Again three phenotypes determined by two alleles (fragments of 7.5 and 3.8 kb) have been observed. Allelic frequencies of the 7.5- and 3.8-kb fragments are 0.24 and 0.76 respectively. The two polymorphic sites are non-randomly associated.

摘要

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