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一名4岁半患有肝脏左外侧叶间叶性错构瘤的男孩:病例报告及文献复习

A 4 and a half years old boy with mesenchymal hamartomas in the left lateral lobe of the liver: A case report and literature review.

作者信息

Liao Wei, Zhang Binhao, Zhang Wei, Chen Lin, Zhang Wanguang, Zhang Bixiang, Chen Xiaoping

机构信息

Hepatic Surgery Center, Department of Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Medicine (Baltimore). 2017 Aug;96(31):e7281. doi: 10.1097/MD.0000000000007281.

DOI:10.1097/MD.0000000000007281
PMID:28767567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5626121/
Abstract

RATIONALE

Mesenchymal hamartomas of the liver is one type of rare liver tumor.

PATIENT CONCERNS

Mesenchymal hamartomas of the liver (MHL) is rarely reported in the left lobe of the liver in children who are more than 2 years old. It is difficult to distinguish it from liver lesions such as hepatoblastoma in children, and hepatocellular carcinoma and focal nodular hyperplasia in adults. In addition, it is hard to correctly diagnose it without pathological examination.

DIAGNOSES

Mesenchymal hamartomas of the liver.

INTERVENTIONS

This patient underwent an operation assisted by the Da Vinci surgical system and the tumor was completely resected.

OUTCOMES

No tumor recurrence or metastasis was observed 14 months after operation.

LESSONS

MHL is a benign tumor that is difficult to diagnose due to the lack of specific clinical symptoms and signs. The management of MHL remains controversial. To achieve a good long-term outcome, complete resection of MHL is recommended.

摘要

理论依据

肝间叶性错构瘤是一种罕见的肝脏肿瘤。

患者情况

2岁以上儿童肝左叶的肝间叶性错构瘤(MHL)鲜有报道。在儿童中,它很难与肝母细胞瘤等肝脏病变区分开来,在成人中则难以与肝细胞癌和局灶性结节性增生区分。此外,未经病理检查很难正确诊断。

诊断

肝间叶性错构瘤。

干预措施

该患者在达芬奇手术系统辅助下接受了手术,肿瘤被完全切除。

结果

术后14个月未观察到肿瘤复发或转移。

经验教训

MHL是一种良性肿瘤,由于缺乏特异性临床症状和体征,难以诊断。MHL的治疗仍存在争议。为获得良好的长期预后,建议完整切除MHL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/c25ad4caff87/medi-96-e7281-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/b687fabb3053/medi-96-e7281-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/96f10d9e76f7/medi-96-e7281-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/c6d5da66f0d2/medi-96-e7281-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/c2e9a85b004b/medi-96-e7281-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/c25ad4caff87/medi-96-e7281-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/b687fabb3053/medi-96-e7281-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/96f10d9e76f7/medi-96-e7281-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/c6d5da66f0d2/medi-96-e7281-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/c2e9a85b004b/medi-96-e7281-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59fe/5626121/c25ad4caff87/medi-96-e7281-g006.jpg

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ACG Case Rep J. 2015 Jul 9;2(4):258-60. doi: 10.14309/crj.2015.78. eCollection 2015 Jul.
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Methylation status of the chromosome arm 19q MicroRNA cluster in sporadic and androgenetic-Biparental mosaicism-associated hepatic mesenchymal hamartoma.
Radiologe. 2018 Jan;58(1):3-9. doi: 10.1007/s00117-017-0333-9.
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Differential diagnosis and management of liver tumors in infants.婴儿肝脏肿瘤的鉴别诊断与管理
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