Bahador A, Geramizadeh B, Rezazadehkermani M, Moslemi S
Departments of Pediatrics Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.
Departments of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Organ Transplant Med. 2014;5(2):78-80.
Mesenchymal hamartoma and hepatoblastoma are common causes of hepatic masses in pediatric population; they have similar radiologic and pathologic features. Herein, we present a case of mesenchymal hamartoma that was preoperatively diagnosed as hepatoblastoma. The mass was completely resected instead of being treated with preoperative chemotherapy. Postoperative pathological evaluation revealed mesenchymal hamartoma with free margins; the patient incidentally received the standard treatment. If we would have measured serum AFP in our patient, we could make the correct diagnosis preoperatively, because AFP increases largely in hepatoblastoma. When suspicious exists, serum AFP is a good guide in differentiating hepatoblastoma from mesenchymal hamartoma.
间叶性错构瘤和肝母细胞瘤是儿童肝肿块的常见病因；它们具有相似的放射学和病理学特征。在此，我们报告一例术前被诊断为肝母细胞瘤的间叶性错构瘤病例。该肿块被完整切除，而非接受术前化疗。术后病理评估显示切缘阴性的间叶性错构瘤；该患者意外接受了标准治疗。如果我们对该患者检测血清甲胎蛋白（AFP），就能在术前做出正确诊断，因为肝母细胞瘤中AFP会大幅升高。当存在可疑情况时，血清AFP是鉴别肝母细胞瘤和间叶性错构瘤的良好指标。
