Bounias M, Nizeyimana B, Vago C
C R Acad Sci III. 1986;303(7):285-9.
A study of the action of very low doses of the delta-endotoxin of Bacillus thuringiensis israëlensis on the larvae of Aedes aegypti (Diptera) gave evidence for peculiar properties of the dose/effect relations based on the variations of the regression slopes of functional relationships between the pairs cysteine/serine and fatty acids/histidine, by contrast with the pair fatty acids/glucose which exhibited a classical shaped relation. This indicates "crypto-toxicological" processes, not lethal by themselves and without pathological symptoms, but able to initiate "pathogen-chaining" mechanisms leading, at the end, to a lethal secondary syndrome.
一项关于极低剂量苏云金芽孢杆菌以色列亚种δ-内毒素对埃及伊蚊（双翅目）幼虫作用的研究表明，基于半胱氨酸/丝氨酸和脂肪酸/组氨酸对之间功能关系的回归斜率变化，剂量/效应关系具有特殊性质，这与脂肪酸/葡萄糖对呈现的经典形状关系形成对比。这表明存在“隐毒理学”过程，这些过程本身并非致命且无病理症状，但能够启动“病原体连锁”机制，最终导致致命的继发综合征。
