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基于简化 SRS-Schwab 成人脊柱畸形分类的脊柱骨盆变化:与退行性脊柱疾病成年患者的残疾和健康相关生活质量的关系。

Spinopelvic Changes Based on the Simplified SRS-Schwab Adult Spinal Deformity Classification: Relationships With Disability and Health-Related Quality of Life in Adult Patients With Prolonged Degenerative Spinal Disorders.

机构信息

Department of Orthopaedics and Traumatology, Central Hospital of Central Finland, Jyväskylä, Finland.

Department of Education and Science, Central Finland Health Care District, Jyväskylä, Finland.

出版信息

Spine (Phila Pa 1976). 2018 Apr 1;43(7):497-502. doi: 10.1097/BRS.0000000000002370.

Abstract

STUDY DESIGN

Cross-sectional, observational study.

OBJECTIVE

To study the occurrence of sagittal malalignment, the adaptability of a simplified sagittal modifiers grading of the Scoliosis Research Society (SRS)-Schwab adult spinal deformity (ASD) classification, and the deformity-specific SRS questionnaire version 30 (SRS-30) in an unselected adult cohort with symptomatic degenerative spinal disorders.

SUMMARY OF BACKGROUND DATA

The sagittal modifiers of the SRS-Schwab ASD classification correlate with health-related quality of life (HRQoL) measures in patients with ASD. The deformities and disabilities caused by sagittal malalignment in patients with common degenerative spinal disorders of multiple etiologies are rarely studied. A simplified and categorizing version of the SRS-Schwab ASD classification in relation to the Oswestry Disability Index (ODI) and the SRS-30 outcomes has not yet been developed.

METHODS

We recruited 874 consecutive patients with degenerative spinal disorders between March 2013 and February 2014. Full spine radiographs were taken and the patients divided into sagittal deformity severity groups: mild or none, moderate, and marked deformity. Participants completed the ODI, SRS-30, and a general health questionnaire.

RESULTS

We included 637 patients in the analysis. The severity of sagittal deformity was mild or none in 407 (63.9%) patients, moderate in 159 (25.0%), and marked in 71 (11.1%). Linearity across the modifier grades and deformity classes was found for ODI total score (P = 0.033), and the function/activity (P = 0.004) and self-image/appearance (P = 0.030) domains of the SRS-30. Age, body mass index, duration of symptoms, and the use of painkillers increased while physical activity, working, and educational status decreased significantly with deformity severity.

CONCLUSION

Sagittal spinopelvic malalignment is significantly related to deterioration of the ODI and the SRS-30 in symptomatic adults with degenerative spinal disorders. The SRS-Schwab classification sagittal modifiers categorized into three groups is a practical tool to detect various clinically significant grades of deformity in a cohort with no recognized ASD.

LEVEL OF EVIDENCE

摘要

研究设计

横断面观察性研究。

目的

研究矢状面失平衡的发生情况,简化的 SRS-Schwab 脊柱侧凸研究协会(SRS)-施瓦布成人脊柱畸形(ASD)分类矢状面修正分级的适应性,以及特定于畸形的 SRS 问卷 30 版(SRS-30)在有症状退行性脊柱疾病的未选择的成年人群中的应用。

背景资料概要

SRS-Schwab ASD 分类的矢状面修正与 ASD 患者的健康相关生活质量(HRQoL)测量相关。由多种病因的常见退行性脊柱疾病引起的矢状面失平衡导致的畸形和残疾很少被研究。尚未开发出与 Oswestry 残疾指数(ODI)和 SRS-30 结果相关的简化和分类 SRS-Schwab ASD 分类版本。

方法

我们于 2013 年 3 月至 2014 年 2 月招募了 874 例退行性脊柱疾病连续患者。拍摄全脊柱 X 线片,并将患者分为矢状面畸形严重程度组:轻度或无、中度和重度畸形。参与者完成了 ODI、SRS-30 和一般健康问卷。

结果

我们对 637 例患者进行了分析。407 例(63.9%)患者矢状面畸形程度为轻度或无,159 例(25.0%)为中度,71 例(11.1%)为重度。ODI 总分(P=0.033)、功能/活动(P=0.004)和自我形象/外观(P=0.030)领域的修正分级和畸形分类之间存在线性关系。年龄、体重指数、症状持续时间和止痛药使用增加,而体力活动、工作和教育状况显著下降,与畸形严重程度相关。

结论

有症状退行性脊柱疾病的成年人中,矢状面脊柱骨盆失平衡与 ODI 和 SRS-30 的恶化显著相关。将 SRS-Schwab 分类矢状面修正分为三组是一种实用的工具,可用于检测无公认 ASD 的队列中各种具有临床意义的畸形严重程度。

证据水平

3 级。

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