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揭示成人脊柱畸形分期矫正手术后胸椎后凸相互变化的影响。

Unveiling the Impact of Reciprocal Changes in Thoracic Kyphosis After Staged Corrective Surgery in Adult Deformity.

作者信息

Lo Yuan-Shun, Lin Erh-Ti Ernest, Huang Yi-Hsun, Hsieh Hung-Lun, Yeh Chen-Wei, Chen Michael Jian-Wen, Chiang Cheng-Hung, Tsai Chun-Hao, Fong Yi-Chin, Chen Yen-Jen, Chen Hsien-Te, Wei Xue-Peng

机构信息

Division of Spine Surgery, Department of Orthopedic Surgery, China Medical University Beigang Hospital, China Medical University, Yunlin, Taiwan.

Division of Spine Surgery, Department of Orthopedic Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan.

出版信息

Global Spine J. 2025 May 3:21925682251340606. doi: 10.1177/21925682251340606.

DOI:10.1177/21925682251340606
PMID:40317472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12049368/
Abstract

Study DesignRetrospective cohort study.ObjectiveReciprocal changes (RCs) in unfused spinal segments can significantly affect the global alignment after corrective surgery. Identifying radiographic thresholds for guiding surgical strategies is critical for optimizing the outcomes.Materials and MethodsNinety-eight ASD patients who underwent staged surgeries, including lateral lumbar interbody fusion (LLIF) and posterior spinal fusion (PSF), were analyzed. According to the final follow-up image, the patients were classified into balanced (BG) and imbalanced (IG) groups, with IG further stratified into proximal junctional kyphosis/failure (IG-PJK/PJF) and non-PJK/PJF (IG-NPJK/PJF). Radiographic and clinical data were collected preoperatively, postoperatively, and at 2-year follow-up.ResultsThe IG exhibited greater RCs in thoracic kyphosis (TK) and PI-LL mismatch from postoperative to follow-up than the BG ( = .030, = .008). Significant predictors included Age >65.5 y/o (AUC: .672) and Post-PT >17.5° (AUC: .852) for imbalance and Post-TK >34.5° (AUC: .755) for IG-PJK/PJF. IG-PJK/PJF showed poorer ODI scores than BG and IG-NPJK/PJF ( = .021 and = .022, respectively). IG-PJK/PJF showed poorer total SRS-22 scores than IG-NPJK/PJF ( = .021).ConclusionIncreased RCs in TK was associated with adverse outcomes. Extending the upper instrumented vertebra (UIV) to the upper thoracic spine and addressing excessive TK (>34.5°) may improve alignment and reduce complications. Radiographic thresholds can provide actionable guidance in surgical planning.

摘要

研究设计

回顾性队列研究。

目的

未融合脊柱节段的相互变化(RCs)可显著影响矫正手术后的整体对线。确定指导手术策略的影像学阈值对于优化手术效果至关重要。

材料与方法

分析98例行分期手术(包括腰椎侧方椎间融合术(LLIF)和后路脊柱融合术(PSF))的成人脊柱畸形(ASD)患者。根据末次随访影像,将患者分为平衡组(BG)和失衡组(IG),IG组进一步分为近端交界性后凸/失败组(IG-PJK/PJF)和非PJK/PJF组(IG-NPJK/PJF)。收集术前、术后及2年随访时的影像学和临床数据。

结果

与BG组相比,IG组从术后到随访时胸段后凸(TK)和骨盆入射角-腰椎前凸(PI-LL)失配的RCs更大(P = .030,P = .008)。显著预测因素包括年龄>65.5岁(AUC:.672)和术后骨盆倾斜度(Post-PT)>17.5°(AUC:.852)与失衡相关,以及术后TK>34.5°(AUC:.755)与IG-PJK/PJF相关。IG-PJK/PJF组的Oswestry功能障碍指数(ODI)评分比BG组和IG-NPJK/PJF组差(分别为P = .021和P = .022)。IG-PJK/PJF组的脊柱侧凸研究学会-22项问卷(SRS-22)总分比IG-NPJK/PJF组差(P = .021)。

结论

TK中RCs增加与不良预后相关。将上固定椎(UIV)延伸至上胸椎并处理过度TK(>34.5°)可能改善对线并减少并发症。影像学阈值可为手术规划提供可行的指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/3b2ddf1c9d08/10.1177_21925682251340606-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/da5a181ac0fd/10.1177_21925682251340606-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/82ca42519d28/10.1177_21925682251340606-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/128d95b0d97f/10.1177_21925682251340606-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/29002d11bde2/10.1177_21925682251340606-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/3b2ddf1c9d08/10.1177_21925682251340606-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/da5a181ac0fd/10.1177_21925682251340606-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/82ca42519d28/10.1177_21925682251340606-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/128d95b0d97f/10.1177_21925682251340606-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/29002d11bde2/10.1177_21925682251340606-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df4/12049368/3b2ddf1c9d08/10.1177_21925682251340606-fig5.jpg

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