Popa V
Clin Chest Med. 1986 Sep;7(3):367-82.
For almost a quarter of a century, the pharmacology of H1 blockers remained quasi-stagnant, isolated from the rapid evolution of clinical pharmacology. However, exciting new developments concerning the role of histamine in asthma, and special pharmacodynamic features of new H1 blockers, have revived our interest in these drugs.
在将近四分之一个世纪里,H1受体阻滞剂的药理学几乎停滞不前,与临床药理学的快速发展脱节。然而,关于组胺在哮喘中的作用以及新型H1受体阻滞剂的特殊药效学特性的令人兴奋的新进展,重新唤起了我们对这些药物的兴趣。