Cooper J W
N Engl Reg Allergy Proc. 1986 Jul-Aug;7(4):356-61.
The H1-blocking antihistamines pharmacology, pharmacokinetics, uses, toxicity and special precautions are presented. Newer agents may offer advantages of longer half-life and lower levels of sedation and motor impairment. Therapeutic considerations are listed with attention to sustained therapeutic efficacy.
本文介绍了H1阻断型抗组胺药的药理学、药代动力学、用途、毒性及特殊注意事项。新型药物可能具有半衰期更长、镇静和运动功能损害程度更低的优势。文中列出了治疗方面的注意事项,重点关注持续的治疗效果。