Dehdashtian Masoud, Bashirnejad Shiva, Malekian Arash, Aramesh Mohammad Reza, Aletayeb Mohammad Hasan
Department of pediatrics (Neonatal Intensive Care Unit); Imam Khomeini hospital; Ahvaz Jundishapur University of Medical Sciences; Iran.
J Neonatal Surg. 2017 Apr 15;6(2):28. doi: 10.21699/jns.v6i2.506. eCollection 2017 Apr-Jun.
The pathogenesis of congenital diaphragmatic hernia (CDH) is not clear. Risk factors including environmental factors have been implicated in the pathogenesis of few congenital anomalies. We aimed to assess the effect of season on the incidence of CDH and mortality rate in the southwest of Iran.
In this retrospective study, the records of 60 patients with CDH who were admitted at Neonatal Intensive Care Unit (NICU) of Imam Khomeini Hospital of Ahvaz, Iran were evaluated.
Assuming that all the neonates born with CDH in the region reach this hospital, overall CDH prevalence rate was 1.09 per 10 000 total births. Conceptions in spring and summer in this region had statistically significantly higher incidence of CDH. Survival rate in the series was 41.6%.
Seasonal variation has impact on the incidence of CDH. Mortality rate in neonates with CDH is still very high.
先天性膈疝（CDH）的发病机制尚不清楚。包括环境因素在内的风险因素与少数先天性畸形的发病机制有关。我们旨在评估季节对伊朗西南部CDH发病率和死亡率的影响。
在这项回顾性研究中，对伊朗阿瓦士伊玛目霍梅尼医院新生儿重症监护病房（NICU）收治的60例CDH患者的记录进行了评估。
假设该地区所有患有CDH的新生儿都到这家医院就诊，CDH的总体患病率为每10000例总出生数中有1.09例。该地区春季和夏季受孕的CDH发病率在统计学上显著更高。该系列的存活率为41.6%。
季节变化对CDH的发病率有影响。CDH新生儿的死亡率仍然很高。
