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富血小板纤维蛋白在已确诊的干槽症治疗中的应用

Platelet rich fibrin in the management of established dry socket.

作者信息

Chakravarthi Srinivas

机构信息

Department of Oral and Maxillofacial Surgery, Sibar Institute of Dental Sciences, Guntur, India.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2017 Jun;43(3):160-165. doi: 10.5125/jkaoms.2017.43.3.160. Epub 2017 Jun 28.

Abstract

OBJECTIVES

Dry socket may occur secondary to the removal of any tooth. However, most dry socket cases develop in the third molar region. Dry socket is multifactorial in nature and has been treated using various modalities with varying success rates. This study assessed the efficacy of platelet rich fibrin (PRF) in established dry socket.

MATERIALS AND METHODS

Ten patients of either sex aged from 41 to 64 years with established dry socket according to established criteria were treated using PRF. Evaluation was performed by observing the reduction of pain using visual analogue scale, analgesic tablet use over the follow-up period, and healing parameters.

RESULTS

Pain was reduced on the first day in all patients with decreased analgesic use. Pain was drastically reduced during follow-up on the first, second, third, and seventh days with a fall in pain score of 0 to 1 after the first day alone. The pain scores of all patients decreased to 1 by the first day except in one patient, and the scores decreased to 0 in all patients after 48 hours. Total analgesic intake ranged from 2 to 6 tablets (aceclofenac 100 mg per tablet) over the follow-up period of 7 days. Healing was satisfactory in all patients by the end of the seventh day.

CONCLUSION

PRF showed early pain reduction in established dry socket with minimal analgesic intake. No patients had allergic reactions to PRF as it is derived from the patient's own blood. PRF showed good wound healing. Our study suggests that PRF should be considered as a treatment modality for established dry socket.

摘要

目的

任何牙齿拔除后都可能继发干槽症。然而,大多数干槽症病例发生在第三磨牙区域。干槽症本质上是多因素的,并且已经采用了各种治疗方法,成功率各不相同。本研究评估了富血小板纤维蛋白(PRF)在已确诊的干槽症中的疗效。

材料与方法

根据既定标准,对10例年龄在41至64岁之间、已确诊为干槽症的患者使用PRF进行治疗。通过使用视觉模拟量表观察疼痛减轻情况、随访期间止痛片的使用情况以及愈合参数来进行评估。

结果

所有患者在第一天疼痛均减轻,止痛片使用量减少。在随访的第一天、第二天、第三天和第七天,疼痛大幅减轻,仅第一天后疼痛评分就从0降至1。除一名患者外,所有患者的疼痛评分在第一天均降至1,48小时后所有患者的评分均降至0。在7天的随访期内,止痛片总摄入量为2至6片(每片醋氯芬酸100毫克)。到第七天结束时,所有患者的愈合情况均令人满意。

结论

PRF在已确诊的干槽症中显示出早期疼痛减轻,止痛片摄入量最少。由于PRF源自患者自身血液,没有患者对其产生过敏反应。PRF显示出良好的伤口愈合效果。我们的研究表明,PRF应被视为已确诊干槽症的一种治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77af/5529189/a860339d4f24/jkaoms-43-160-g001.jpg

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