Shamriz Oded, Shoenfeld Yehuda
Paediatric Division, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, affiliated to the Sackler Faculty of Medicine Tel-Aviv University, Tel-Aviv, Israel.
Clin Exp Rheumatol. 2017 Nov-Dec;35(6):1037-1042. Epub 2017 Jul 7.
Olfaction plays an important role in the perception of our environment. Smell impairment is known to be a manifestation of several autoimmune diseases. Similarities between the olfactory and immune systems and previously published human studies and animal models of autoimmune diseases account for the accumulating evidence for this observation. In this review, we will present the current literature concerning olfactory dysfunction in autoimmune diseases, discuss clinical aspects and provide new insights regarding pathogenesis and possible mechanisms.
嗅觉在我们对环境的感知中起着重要作用。嗅觉障碍是多种自身免疫性疾病的一种表现。嗅觉系统与免疫系统之间的相似性，以及先前发表的关于自身免疫性疾病的人体研究和动物模型，为这一观察结果提供了越来越多的证据。在这篇综述中，我们将介绍有关自身免疫性疾病中嗅觉功能障碍的当前文献，讨论临床方面，并提供有关发病机制和可能机制的新见解。
