Cameron J S, Challah S
Lancet. 1986 Oct 25;2(8513):962-6. doi: 10.1016/s0140-6736(86)90612-4.
In 1975-84 762 new patients with end-stage renal failure (ESRF) due to diabetes mellitus were accepted onto renal replacement programmes in the United Kingdom. They formed 5.7% of the total intake of ESRF patients. This proportion rose from 1.4% in 1975 to 11.1% in 1984. 4.1% of the patients on renal replacement therapy at the end of 1984 were reported as having ESRF due to diabetic nephropathy. During 1983-84, 272 patients taken on were type I (76%) and 87 (24%) were type II diabetics. Continuous ambulatory peritoneal dialysis (CAPD) was most popular as both initial (51%, plus 24% on intermittent peritoneal dialysis in 1983-84) and long-term treatment (48% of 446 under treatment at Dec 31, 1984); 163 patients (36.5%) had successful allografts, and only 14% of patients were on haemodialysis. Actuarial survival was 49% at 3 years, irrespective of type of treatment; the death rate for type II diabetics approached the intake rate in 1983-84. There was considerable regional variation in the numbers of diabetics on treatment. Even though the proportion of diabetics entering British end-stage renal failure programmes is rising, many patients who may benefit from treatment are probably not receiving it.
1975年至1984年间，英国有762名因糖尿病导致终末期肾衰竭（ESRF）的新患者被纳入肾脏替代治疗项目。他们占ESRF患者总入院人数的5.7%。这一比例从1975年的1.4%升至1984年的11.1%。据报告，1984年底接受肾脏替代治疗的患者中有4.1%因糖尿病肾病导致ESRF。1983年至1984年间，接受治疗的272名患者中，I型糖尿病患者有272名（占76%），II型糖尿病患者有87名（占24%）。持续性非卧床腹膜透析（CAPD）作为初始治疗（1983年至1984年为51%，间歇性腹膜透析为24%）和长期治疗（截至1984年12月31日，446名接受治疗患者中的48%）最为普遍；163名患者（36.5%）进行了成功的同种异体移植，只有14%的患者接受血液透析。无论治疗类型如何，3年精算生存率为49%；II型糖尿病患者的死亡率在1983年至1984年接近入院率。接受治疗的糖尿病患者数量存在显著的地区差异。尽管进入英国终末期肾衰竭项目的糖尿病患者比例在上升，但许多可能从治疗中受益的患者可能并未接受治疗。
