Araújo Marco, Miola Marta, Baldi Giovanni, Perez Javier, Verné Enrica
Colorobbia España S.A, Carretera CV-160, Vilafamés 12192, Spain.
Ce.Ri.Col, Centro Richerche Colorobbia, Via Pietramarina 123, Sovigliana (FI) 50053, Italy.
Materials (Basel). 2016 Mar 24;9(4):226. doi: 10.3390/ma9040226.
Three new silica-based glass formulations with low molar Ca/P ratio (2-3) have been synthesized. The thermal properties, the crystalline phases induced by thermal treatments and the sintering ability of each glass formulation have been investigated by simultaneous differential scanning calorimetry-thermogravimetric analysis (DSC-TG), X-ray diffraction (XRD) and hot stage microscopy (HSM). The glasses exhibited a good sintering behavior, with two samples achieving shrinkage of 85%-95% prior to crystallization. The bioactivity of the glasses in simulated body fluid (SBF) has been investigated by performing XRD and Fourier transform infrared spectroscopy (FTIR) on the samples prior and after immersion. The glasses with lower MgO contents were able to form a fully crystallized apatite layer after three days of immersion in simulated body fluid (SBF), while for the glass exhibiting a higher MgO content in its composition, the crystallization of the Ca-P layer was achieved after seven days. The conjugation of these properties opens new insights on the synthesis of highly bioactive and mechanically strong prosthetic materials.
已合成了三种具有低摩尔钙磷比（2-3）的新型二氧化硅基玻璃配方。通过同步差示扫描量热法-热重分析（DSC-TG）、X射线衍射（XRD）和热台显微镜（HSM）研究了每种玻璃配方的热性能、热处理诱导的晶相以及烧结能力。这些玻璃表现出良好的烧结行为，有两个样品在结晶前收缩率达到85%-95%。通过对浸泡前后的样品进行XRD和傅里叶变换红外光谱（FTIR），研究了玻璃在模拟体液（SBF）中的生物活性。MgO含量较低的玻璃在模拟体液（SBF）中浸泡三天后能够形成完全结晶的磷灰石层，而对于其成分中MgO含量较高的玻璃，在七天后实现了钙磷层的结晶。这些特性的结合为合成高生物活性和机械强度高的假体材料开辟了新的思路。
