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原发性二尖瓣反流超声心动图监测的差异

Variation in the Echocardiographic Surveillance of Primary Mitral Regurgitation.

作者信息

Tanguturi Varsha K, Hidrue Michael K, Picard Michael H, Atlas Steven J, Weilburg Jeffrey B, Ferris Timothy G, Armstrong Katrina, Wasfy Jason H

机构信息

From the Division of Cardiology (V.K.T., M.H.P., J.H.W.), Department of Medicine (V.K.T., M.H.P., J.H.W., S.J.A., K.A.), Massachusetts General Hospital, Harvard Medical School, Boston; and Massachusetts General Physicians Organization, Boston (M.K.H., M.H.P., S.J.A., J.B.W., T.G.F., J.H.W.).

出版信息

Circ Cardiovasc Imaging. 2017 Aug;10(8). doi: 10.1161/CIRCIMAGING.117.006495.

Abstract

BACKGROUND

Clinical outcomes after surgical treatment of mitral regurgitation are worse if intervention occurs after deterioration of left ventricular size and function. Transthoracic echocardiographic (TTE) surveillance of patients with mitral regurgitation is indicated to avoid adverse ventricular remodeling. Overly frequent TTEs can impair patient access and reduce value in care delivery. This balance between timely surveillance and overutilization of TTE in valvular disease provides a model to study variation in the delivery of healthcare services. We investigated patient and provider factors contributing to variation in TTE utilization and hypothesized that variation was attributable to provider practice even after adjustment for patient characteristics.

METHODS AND RESULTS

We obtained records of all TTEs from 2001 to 2016 completed at a large echocardiography laboratory. The outcome variable was time interval between TTEs. We constructed a mixed-effects linear regression model with the individual physician as the random effect in the model and used intraclass correlation coefficient to assess the proportion of outcome variation because of provider practice. Our study cohort was 55 773 TTEs corresponding to 37 843 intervals ordered by 635 providers. The mean interval between TTEs was 12.4 months, 17.0 months, 18.3 months, and 17.4 months for severe, moderate, mild, and trace mitral regurgitation, respectively, with 20% of providers deemed overutilizers of TTEs and 25% underutilizers.

CONCLUSIONS

We conclude that there is substantial variation in follow-up intervals for TTE assessment of mitral regurgitation, despite risk-adjustment for patient variables, likely because of provider factors.

摘要

背景

如果在左心室大小和功能恶化后进行干预,二尖瓣反流手术治疗后的临床结果会更差。对二尖瓣反流患者进行经胸超声心动图(TTE)监测有助于避免不良的心室重塑。过于频繁的TTE检查会影响患者就医,并降低医疗服务价值。瓣膜病中TTE检查在及时监测与过度使用之间的这种平衡为研究医疗服务提供中的差异提供了一个模型。我们调查了导致TTE使用差异的患者和医疗服务提供者因素,并假设即使在对患者特征进行调整后,差异仍归因于医疗服务提供者的做法。

方法和结果

我们获取了2001年至2016年在一家大型超声心动图实验室完成的所有TTE检查记录。结果变量是两次TTE检查之间的时间间隔。我们构建了一个混合效应线性回归模型,将个体医生作为模型中的随机效应,并使用组内相关系数来评估因医疗服务提供者做法导致的结果差异比例。我们的研究队列包括55773次TTE检查,对应于635名医疗服务提供者开出的37843个检查间隔。重度、中度、轻度和微量二尖瓣反流患者两次TTE检查之间的平均间隔分别为12.4个月、17.0个月、18.3个月和17.4个月,20%的医疗服务提供者被视为TTE检查的过度使用者,25%为使用不足者。

结论

我们得出结论,尽管对患者变量进行了风险调整,但二尖瓣反流TTE评估的随访间隔仍存在很大差异,这可能是由于医疗服务提供者因素导致的。

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