Davendralingam Natasha, Davagnanam Indran, Stidworthy Mark Frederick, Baldrey Vicki, Peters Laureen Michele, Stapleton Nadene
Department of Radiology, Royal London Hospital, London, UK.
Department of Radiology, Barts and The London School of Medicine and Dentistry, London, UK.
Vet Rec. 2017 Aug 3. doi: 10.1136/vr.104250.
A three-year-old ferret presented with a three-month history of rapid clinical deterioration necessitating euthanasia shortly after initial veterinary assessment. Postmortem PCR testing confirmed which is most commonly identified in amphibians, reptiles and aquatic life. Infection of a captive-bred domestic ferret is highly unusual. A collaborative effort involving medical doctors, clinical veterinarians and veterinary pathologists investigated the potential sources of human-animal, animal-animal and environmental-animal transmission. No human-animal or animal-animal risks were identified. As the affected ferret was the only ferret to have regular exposure to the owner's aquarium, a postmortem study of a dead guppy and aquarium water analysis were performed which confirmed mycobacteriosis. Although was not specifically cultured, as a slow-growing organism, may have been outgrown by more rapidly growing mycobacteria or Gram-positive bacilli present in the water. Thus, transmission of via aquarium exposure was certainly plausible. This is the second documented case of in a ferret and the first to determine a source of infection. This report highlights the previously recognised risk of mycobacterial exposure from aquaria and that caution is required before allowing domestic ferrets to have contact with potentially infected water reservoirs due to its fatal nature in this vulnerable species.
一只三岁的雪貂出现了三个月的快速临床恶化病史，在初次兽医评估后不久就需要实施安乐死。尸检PCR检测证实了……，这种情况最常见于两栖动物、爬行动物和水生生物中。圈养繁殖的家养雪貂感染这种情况非常罕见。一个由医生、临床兽医和兽医病理学家共同参与的团队调查了人传人、动物传动物以及环境传动物的潜在传播源。未发现人传人或动物传动物的风险。由于受感染的雪貂是唯一经常接触主人水族箱的雪貂，因此对一条死孔雀鱼进行了尸检研究并对水族箱水进行了分析，结果证实了分枝杆菌病。尽管……未被专门培养出来，但作为一种生长缓慢的生物体，它可能被水中生长更快的分枝杆菌或革兰氏阳性杆菌超过。因此，通过水族箱接触传播……当然是有可能的。这是雪貂感染……的第二例有记录的病例，也是第一例确定感染源的病例。本报告强调了先前已认识到的水族箱分枝杆菌暴露风险，并且由于这种情况对这个脆弱物种具有致命性，在允许家养雪貂接触潜在受感染的水源之前需要谨慎。
