Barth Stefanie A, Menge Christian, Hillemann Doris, Lauda Alexander, Pfleghaar Stephan
Friedrich-Loeffler-Institut/Bundesforschungsinstitut für Tiergesundheit, Institut für molekulare Pathogenese.
Nationales Referenzlabor für Tuberkulose der Rinder.
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2020 Feb;48(1):50-55. doi: 10.1055/a-1069-6630. Epub 2020 Feb 14.
A 9-month old pet ferret was presented to a veterinarian with symptoms of weight loss, apathy, and hyporexia. Explorative laparotomy identified a firm mass of approximately 2 × 2 × 2 cm in size in the mesentery of the jejunum. Because of the poor general condition and the unfavorable prognosis, the ferret was euthanized during surgery. The mass was resected in total and submitted to histological examination which revealed a granulomatous and necrotizing lymphadenitis. Acid fast bacteria were detected by Fite-Faraco staining leading to the suspicion of an infection with sp. PCR confirmed presence of DNA of members of the complex, subsequently specified as . The detected spoligotype SB2548 was described for the first time. Ferrets are presented to veterinarians with increasing frequency because of their growing popularity as pet animals. Since these animals are highly susceptible to mycobacterial infections, mycobacteriosis and especially zoonotic relevant tuberculosis should be considered as differential diagnosis.
一只9个月大的宠物雪貂因体重减轻、冷漠和食欲减退的症状被送至兽医处。剖腹探查术发现空肠系膜中有一个大小约为2×2×2厘米的坚实肿块。由于总体状况不佳且预后不良，雪貂在手术过程中被安乐死。肿块被完整切除并送去做组织学检查，结果显示为肉芽肿性坏死性淋巴结炎。通过菲-法拉科染色检测到抗酸菌，怀疑感染了分枝杆菌属。聚合酶链反应证实存在分枝杆菌复合体成员的DNA，随后确定为。检测到的寡核苷酸分型SB2548为首次报道。由于雪貂作为宠物越来越受欢迎，它们被送至兽医处的频率也在增加。由于这些动物极易感染分枝杆菌，分枝杆菌病尤其是与人畜共患病相关的结核病应被视为鉴别诊断。
