de Freitas J C, Sawaya M I
Toxicon. 1986;24(8):751-5. doi: 10.1016/0041-0101(86)90099-1.
Caissarone (mol. wt 229.5; melting point 285-290 degrees C) is a novel purine isolated and purified from the sea-anemone Bunodosoma caissarum. The purine inhibits the detachment of the vitelline layer from the sea-urchin egg plasma membrane after fertilization and this effect leads to polyspermy. Various abnormalities were detected at various embryonic stages, from multipolar egg division through unequal cleavages and exogastrulation up to teratogenic effects on the sea-urchin larvae (echinopluteus).
凯萨罗宁(分子量229.5;熔点285 - 290摄氏度)是从海葵凯氏列指海葵中分离纯化出的一种新型嘌呤。这种嘌呤会抑制受精后卵黄膜与海胆卵质膜的分离,这种作用会导致多精入卵。在从多极卵裂到不等裂、外胚层外翻直至对海胆幼虫(长腕幼虫)产生致畸作用的各个胚胎阶段都检测到了各种异常情况。