O'Hara D A, Fragen R J, Shanks C A
Br J Anaesth. 1986 Nov;58(11):1300-2. doi: 10.1093/bja/58.11.1300.
This study evaluated train-of-four recovery after the administration of vecuronium, comparing measured with visually observed responses. Responses to supramaximal stimuli of the ulnar nerves were measured by a force transducer, and compared with visually observed movements of the contralateral thumb. For the 10 patients anaesthetized with nitrous oxide and enflurane, the second, third and fourth twitches visually reappeared at 84 (+/- 10)%, 76 (+/- 11)%, and 70 (+/- 12)% measured blockade, respectively. For the other 10 patients, anaesthetized with a narcotic-barbiturate technique, the second, third and fourth twitches reappeared at 81 (+/- 8)%, 68 (+/- 9)%, and 59 (+/- 11)%. These results were not different for the two anaesthetic techniques.
本研究评估了维库溴铵给药后的四个成串刺激恢复情况，比较了测量反应与视觉观察反应。通过力传感器测量尺神经超强刺激的反应，并与对侧拇指的视觉观察运动进行比较。对于10例接受氧化亚氮和安氟醚麻醉的患者，第二、第三和第四次肌颤搐在测量的阻滞分别达到84（±10）%、76（±11）%和70（±12）%时视觉上重新出现。对于另外10例采用麻醉性巴比妥类技术麻醉的患者，第二、第三和第四次肌颤搐分别在81（±8）%、68（±9）%和59（±11）%时重新出现。两种麻醉技术的这些结果没有差异。
