Shintaku Sadanori, Kawanishi Hideki, Moriishi Misaki, Ago Rika, Banshodani Masataka, Hashimoto Shinji, Tsuchiya Shinichiro
Department of Artificial Organs, Tsuchiya General Hospital, Hiroshima - Japan.
Faculty of Medicine, Hiroshima University, Hiroshima - Japan.
J Vasc Access. 2017 Sep 11;18(5):371-378. doi: 10.5301/jva.5000777. Epub 2017 Aug 2.
Early access failure is an important complication of autogenous arteriovenous fistulas (AVFs). We prospectively monitored patients who underwent AVF creation using ultrasonography.
Color flow imaging was used to assess access blood flow in patients undergoing creation of a new AVF in the distal forearm preoperatively and at 1 day and 1 week postoperatively. We measured the flow volume (FV) and resistive index (RI) of the brachial artery, and the internal diameter of the brachial artery and outflow vein. The primary outcome was the primary patency of the AVF without percutaneous angioplasty (PTA) or surgical revision 40 days after access creation.
We recruited 35 patients with newly created AVFs (men, 21; mean age, 73 years). Within one day of operation, the overall FV increased from 62 to 352 mL/min (p<0.0001) while the overall RI decreased from 1.0 to 0.63 (p<0.001). Five patients required PTA or surgical revision (intervention group [IG]), whereas 30 patients did not (non-intervention group [NIG]). The FV increased while the RI decreased from day 1 to week 1 in the NIG, but not in the IG (p<0.0001). The diameter of the brachial artery and outflow vein significantly increased in the NIG at 1 week. The FV of 235 mL/min and RI of 0.63 at 1 day were the thresholds for predicting early fistula failure.
Access FV and RI at 1 day after AVF creation can predict primary patency and help plan intervention.
早期通路失败是自体动静脉内瘘(AVF)的一种重要并发症。我们前瞻性地使用超声对接受AVF造瘘的患者进行监测。
采用彩色血流成像技术,在术前、术后1天和1周对前臂远端接受新AVF造瘘的患者的通路血流进行评估。我们测量了肱动脉的血流量(FV)和阻力指数(RI),以及肱动脉和流出静脉的内径。主要结局是通路建立40天后,AVF在未进行经皮血管成形术(PTA)或手术修复情况下的初始通畅率。
我们招募了35例新建立AVF的患者(男性21例;平均年龄73岁)。术后1天内,总体FV从62 mL/min增加至352 mL/min(p<0.0001),而总体RI从1.0降至0.63(p<0.001)。5例患者需要PTA或手术修复(干预组[IG]),而30例患者不需要(非干预组[NIG])。NIG组从术后1天到1周FV增加而RI降低,但IG组并非如此(p<0.0001)。NIG组在术后1周时肱动脉和流出静脉直径显著增加。术后1天FV为235 mL/min和RI为0.63是预测早期内瘘失败的阈值。
AVF建立后1天的通路FV和RI可预测初始通畅率,并有助于制定干预计划。