• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

上下层:人多能干细胞来源的心房和心室心肌细胞。

Upstairs, Downstairs: Atrial and Ventricular Cardiac Myocytes from Human Pluripotent Stem Cells.

机构信息

British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.

出版信息

Cell Stem Cell. 2017 Aug 3;21(2):151-152. doi: 10.1016/j.stem.2017.07.006.

DOI:10.1016/j.stem.2017.07.006
PMID:28777937
Abstract

Cardiomyocyte creation by human pluripotent stem cells (hPSCs) has generated opportunities for heart repair, disease modeling, and drug development. In this issue of Cell Stem Cell,Lee et al. (2017) report prospective markers of atrial versus ventricular myocyte formation from hPSCs and their use in directed differentiation of cardiac sub-lineages.

摘要

人多能干细胞(hPSCs)产生的心肌细胞为心脏修复、疾病建模和药物开发提供了新的机会。在本期的《Cell Stem Cell》杂志上,Lee 等人(2017)报道了 hPSC 中鉴定心房间质细胞与心室内质细胞形成的前瞻性标志物,以及它们在心脏亚谱系定向分化中的应用。

相似文献

1
Upstairs, Downstairs: Atrial and Ventricular Cardiac Myocytes from Human Pluripotent Stem Cells.上下层:人多能干细胞来源的心房和心室心肌细胞。
Cell Stem Cell. 2017 Aug 3;21(2):151-152. doi: 10.1016/j.stem.2017.07.006.
2
Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations.人多能干细胞衍生的心房和心室心肌细胞来源于不同的中胚层细胞群体。
Cell Stem Cell. 2017 Aug 3;21(2):179-194.e4. doi: 10.1016/j.stem.2017.07.003.
3
Modeling human multi-lineage heart field development with pluripotent stem cells.利用多能干细胞模拟人类多谱系心脏场发育
Cell Stem Cell. 2022 Sep 1;29(9):1382-1401.e8. doi: 10.1016/j.stem.2022.08.007.
4
Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts.人多能干细胞的心肌特化:人类心脏移植物的快速生产。
Biomaterials. 2016 Aug;98:64-78. doi: 10.1016/j.biomaterials.2016.04.003. Epub 2016 Apr 26.
5
Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes.从心室和心房人多能干细胞来源的心肌细胞生成环形工程心脏组织。
Nat Commun. 2020 Jan 7;11(1):75. doi: 10.1038/s41467-019-13868-x.
6
LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells.LEFTY-PITX2 信号通路对于人类多能干细胞来源的心脏中胚层细胞中成熟和心室类心脏器官的产生至关重要。
Biomaterials. 2021 Nov;278:121133. doi: 10.1016/j.biomaterials.2021.121133. Epub 2021 Sep 21.
7
Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells.肌球蛋白轻链 2 标记来自人胚胎干细胞的分化心室心肌细胞。
Pflugers Arch. 2021 Jul;473(7):991-1007. doi: 10.1007/s00424-021-02578-3. Epub 2021 May 24.
8
Human Pluripotent Stem Cell-Derived Cardiovascular Cells: From Developmental Biology to Therapeutic Applications.人多能干细胞衍生的心血管细胞:从发育生物学到治疗应用。
Cell Stem Cell. 2019 Sep 5;25(3):311-327. doi: 10.1016/j.stem.2019.07.010.
9
Human cardiomyocyte generation from pluripotent stem cells: A state-of-art.从多能干细胞生成人类心肌细胞:最新进展。
Life Sci. 2016 Jan 15;145:98-113. doi: 10.1016/j.lfs.2015.12.023. Epub 2015 Dec 10.
10
Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia.开发一种稳健的诱导多能干细胞心房肌细胞分化方案,以模拟心房性心律失常。
Stem Cell Res Ther. 2023 Jul 27;14(1):183. doi: 10.1186/s13287-023-03405-5.

引用本文的文献

1
Promises and Challenges of Organoid-Guided Precision Medicine.类器官指导的精准医学的前景与挑战。
Med. 2021 Sep 10;2(9):1011-1026. doi: 10.1016/j.medj.2021.08.005.
2
Disease Modeling and Disease Gene Discovery in Cardiomyopathies: A Molecular Study of Induced Pluripotent Stem Cell Generated Cardiomyocytes.心肌疾病的疾病建模和疾病基因发现:诱导多能干细胞生成的心肌细胞的分子研究。
Int J Mol Sci. 2021 Mar 24;22(7):3311. doi: 10.3390/ijms22073311.
3
Recent Advancements in Engineering Strategies for Manipulating Neural Stem Cell Behavior.
用于调控神经干细胞行为的工程策略的最新进展
Curr Tissue Microenviron Rep. 2020 Jun;1(2):41-47. doi: 10.1007/s43152-020-00003-y. Epub 2020 Apr 3.
4
In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix.通过 FGF4 和细胞外基质在体外生成功能性鼠类心脏类器官。
Nat Commun. 2020 Sep 3;11(1):4283. doi: 10.1038/s41467-020-18031-5.
5
Spatiotemporal Control of Morphogen Delivery to Pattern Stem Cell Differentiation in Three-Dimensional Hydrogels.三维水凝胶中形态发生素传递的时空控制以调控干细胞分化模式
Curr Protoc Stem Cell Biol. 2019 Dec;51(1):e97. doi: 10.1002/cpsc.97.
6
Spatiotemporal control and modeling of morphogen delivery to induce gradient patterning of stem cell differentiation using fluidic channels.利用流道控制和模拟形态发生因子的时空传递,诱导干细胞分化的梯度模式。
Biomater Sci. 2019 Mar 26;7(4):1358-1371. doi: 10.1039/c8bm01199k.