上下层：人多能干细胞来源的心房和心室心肌细胞。
Upstairs, Downstairs: Atrial and Ventricular Cardiac Myocytes from Human Pluripotent Stem Cells.
机构信息
British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
出版信息
Cell Stem Cell. 2017 Aug 3;21(2):151-152. doi: 10.1016/j.stem.2017.07.006.
PMID:28777937
Abstract
Cardiomyocyte creation by human pluripotent stem cells (hPSCs) has generated opportunities for heart repair, disease modeling, and drug development. In this issue of Cell Stem Cell,Lee et al. (2017) report prospective markers of atrial versus ventricular myocyte formation from hPSCs and their use in directed differentiation of cardiac sub-lineages.
摘要
人多能干细胞（hPSCs）产生的心肌细胞为心脏修复、疾病建模和药物开发提供了新的机会。在本期的《Cell Stem Cell》杂志上，Lee 等人（2017）报道了 hPSC 中鉴定心房间质细胞与心室内质细胞形成的前瞻性标志物，以及它们在心脏亚谱系定向分化中的应用。
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