The Risks Associated with Red Blood Cell Transfusion: Implications for Critical Care Practice.

This systematic literature review informs the clinician caring for the critically ill patient of the risks associated with red blood cell (RBC) transfusion. Data were extracted from publications between 2008 and 2016 and were reviewed to determine their usefulness in providing evidence associated with the risk of receiving an RBC transfusion. They reveal that this intervention may exacerbate certain clinical conditions and increase mortality and morbidity rates. Further scientific study is needed to better inform clinical practitioners about the inherent risks and benefits associated with the common clinical intervention of RBC transfusion in the critically ill patient.