Department of Dermatology, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard #MC-9190, Dallas, TX 75390-7208, USA.
Obstet Gynecol Clin North Am. 2017 Sep;44(3):407-420. doi: 10.1016/j.ogc.2017.04.004.
Lichen planus is an inflammatory mucocutaneous condition with a myriad of clinical manifestations. There are 3 forms of lichen planus that effect the vulva: papulosquamous, hypertrophic, and erosive. Erosive lichen planus can progress to vulvar scaring, vaginal stenosis, and squamous cell carcinoma; these long-term sequelae cause sexual distress, depression, and decreased quality of life for patients. Diagnosis is often delayed because of patient embarrassment or clinician misdiagnosis. Early recognition and treatment is essential to decreasing the morbidity of this condition. Multimodal treatment, along with a multidisciplinary approach, will improve outcomes and further clinical advances in studying this condition.
扁平苔藓是一种具有多种临床表现的炎症性黏膜疾病。有 3 种形式的扁平苔藓会影响外阴:丘疹鳞屑性、肥厚性和糜烂性。糜烂性扁平苔藓可进展为外阴瘢痕、阴道狭窄和鳞状细胞癌;这些长期后果会导致患者的性困扰、抑郁和生活质量下降。由于患者的尴尬或临床医生的误诊,诊断常常被延误。早期识别和治疗对于降低这种疾病的发病率至关重要。多模式治疗以及多学科方法将改善这种疾病的治疗效果,并促进对该疾病的进一步临床研究。