Goh J W, Ho-Asjoe M, Sastry B R
Gen Pharmacol. 1986;17(5):537-42. doi: 10.1016/0306-3623(86)90089-3.
Tetanus-induced (400 Hz, 200 pulses) long-lasting potentiation of the stratum radiatum-evoked CA1 population spike in hippocampal slices is not accompanied by any change in Na+-independent [3H]glutamate binding sites. Homosynaptic depression that occurs subsequent to either a low frequency tetanus (20 Hz, 600 pulses) or a transient exposure to Cl(-)-free (containing NO3-) medium is associated with an elevation in the amino acid binding. [3H]Glutamate uptake into slices was decreased following a high frequency (400 Hz, 200 pulses) tetanus but in the majority of cases was increased following a low frequency (20 Hz, 600 pulses) tetanus to stratum radiatum. When the high frequency tetanus was given in the absence of extracellular Ca2+, there was a further reduction in [3H]glutamate uptake.
破伤风诱导（400赫兹，200个脉冲）海马切片辐射层诱发的CA1群体峰电位的长时程增强，并未伴随不依赖钠离子的[3H]谷氨酸结合位点的任何变化。在低频破伤风（20赫兹，600个脉冲）或短暂暴露于无氯（含硝酸根）培养基后出现的同突触抑制，与氨基酸结合的升高有关。高频（400赫兹，200个脉冲）破伤风后，切片对[3H]谷氨酸的摄取减少，但在大多数情况下，低频（20赫兹，600个脉冲）辐射层破伤风后摄取增加。当在无细胞外钙离子的情况下给予高频破伤风时，[3H]谷氨酸摄取进一步减少。
