Department of Anesthesiology and Pain Management, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9068, USA.
Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
J Racial Ethn Health Disparities. 2018 Jun;5(3):632-637. doi: 10.1007/s40615-017-0409-2. Epub 2017 Aug 4.
Total joint arthroplasty is an effective treatment for osteoarthritis-related symptoms not resolved with non-surgical therapy. There is a growing body of evidence supporting the use of neuraxial anesthesia for these surgical procedures. We utilized the American College of Surgeons-National Surgical Quality Improvement Program database to study the effects of race on the type of anesthesia and postoperative outcomes in elective total joint replacement surgery.
We included African-American and White adult patients (age > 18 years) undergoing elective primary total knee or hip arthroplasty under general or neuraxial (spinal or epidural) anesthesia (2005-2013). A 1:3 matched sample of African-American vs. White patients was created based on propensity scores. The differences in anesthetic technique and postoperative complications between the two groups were evaluated before and after matching.
A total of 102,122 patients were included. African-American patients were younger (mean ± standard deviation, 62.08 ± 11.17 vs. 66.37 ± 10.53 years, p < 0.001) and had a lower modified Charlson comorbidity index (CCI) score (3.07 ± 1.39 vs. 3.42 ± 1.33, p < 0.001). General anesthesia was used more commonly in the African-American patients group (64.56 vs. 62.25%, p < 0.001). However, when the two groups were matched, the differences in the type of anesthesia disappeared (odds ratio [OR] 0.96, 95% confidence limits [CL] 0.85-1.08, p = 0.455). African-American patients had a higher rate of 30-day postoperative complications before matching (3.08 vs. 2.20%, p < 0.001) and after matching (3.63 vs. 2.33%) (OR 1.58, 95% CL 1.13-2.21, p = 0.007).
There is no significant difference in the type of anesthesia received for total joint arthroplasty between African-American and White patients; however, there is a disparity in the postoperative outcomes in favor of the White patient group. Further studies needed to explain the reasons for these findings.
全关节置换术是一种治疗非手术治疗无法缓解的骨关节炎相关症状的有效方法。越来越多的证据支持在这些手术中使用椎管内麻醉。我们利用美国外科医师学会-国家手术质量改进计划数据库研究种族对择期全关节置换手术中麻醉类型和术后结果的影响。
我们纳入了年龄大于 18 岁的接受全身麻醉或椎管内麻醉(脊髓或硬膜外)的择期初次全膝关节或全髋关节置换术的非裔美国人和白人成年患者(2005-2013 年)。根据倾向评分,创建了非裔美国人和白人患者的 1:3 匹配样本。在匹配前后评估了两组之间麻醉技术和术后并发症的差异。
共纳入 102122 例患者。非裔美国患者年龄较小(平均值±标准差,62.08±11.17 岁比 66.37±10.53 岁,p<0.001),改良 Charlson 合并症指数(CCI)评分较低(3.07±1.39 比 3.42±1.33,p<0.001)。非裔美国患者组更常使用全身麻醉(64.56%比 62.25%,p<0.001)。然而,当两组匹配后,麻醉类型的差异消失(比值比 [OR] 0.96,95%置信区间 [CL] 0.85-1.08,p=0.455)。在匹配前(3.08%比 2.20%,p<0.001)和匹配后(3.63%比 2.33%),非裔美国患者术后 30 天并发症发生率更高(OR 1.58,95% CL 1.13-2.21,p=0.007)。
非裔美国人和白人患者全关节置换术接受的麻醉类型无显著差异;然而,术后结果存在差异,白人患者组更有利。需要进一步的研究来解释这些发现的原因。