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难民妇女的妊娠期糖尿病护理和结局:基于人群的队列研究。

Gestational diabetes care and outcomes for refugee women: a population-based cohort study.

机构信息

Department of Medicine, University of Toronto.

Institute for Clinical Evaluative Sciences.

出版信息

Diabet Med. 2017 Nov;34(11):1608-1614. doi: 10.1111/dme.13440. Epub 2017 Aug 23.

Abstract

AIM

To determine the prevalence of adverse clinical outcomes, the rates of healthcare utilization, and the incidence of post-partum Type 2 diabetes in refugees with gestational diabetes (GDM), compared with other immigrants and non-immigrants.

METHODS

A population-based cohort study was conducted using healthcare databases in Ontario, Canada. Over 40 000 women with GDM having singleton live births between 2002 and 2014 were identified. We identified GDM adverse outcomes such as macrosomia, pre-eclampsia and respiratory distress syndrome. Antenatal and newborn healthcare utilization were ascertained. Women were then followed for diagnosis of diabetes post-partum.

RESULTS

Both refugees and other immigrants had a lower rate than non-immigrants of many adverse GDM outcomes, including pre-eclampsia [relative risk (RR) 0.65, 95% confidence interval (95% CI) 0.44-0.95 and 0.61, 95% CI 0.52-0.72, respectively], preterm birth (RR 0.87, 95% CI 0.75-0.995 and 0.85, 95% CI 0.80-0.91, respectively), and respiratory distress syndrome (RR 0.83, 95% CI 0.70-0.97 and 0.78, 95% CI 0.72-0.84, respectively). However, refugees were less likely to attend well-baby care in time for the first routine vaccination (RR 0.92, 95% CI 0.88-0.95). Incidence of post-partum diabetes was high in all groups, but refugee women were at increased risk (hazard ratio 1.23, 95% CI 1.11-1.37).

CONCLUSIONS

Despite different circumstances leading to migration, refugees have a similar 'healthy immigrant effect' to other immigrants, with respect to adverse GDM outcomes. However, newborns of refugees were less likely to have well-baby care, and refugee women were also at especially high risk of developing diabetes post-partum. These are both important public health issues.

摘要

目的

确定患有妊娠期糖尿病(GDM)的难民与其他移民和非移民相比,不良临床结局的发生率、医疗保健利用率和产后 2 型糖尿病的发病率。

方法

本研究采用加拿大安大略省的医疗保健数据库进行了一项基于人群的队列研究。在 2002 年至 2014 年间,共确定了 40000 多名患有单胎活产 GDM 的女性。我们确定了 GDM 的不良结局,如巨大儿、子痫前期和呼吸窘迫综合征。确定了产前和新生儿的医疗保健利用率。随后对这些女性进行了产后糖尿病的诊断随访。

结果

与非移民相比,难民和其他移民 GDM 的许多不良结局发生率较低,包括子痫前期[相对风险(RR)0.65,95%置信区间(95%CI)0.44-0.95 和 0.61,95%CI 0.52-0.72]、早产[RR 0.87,95%CI 0.75-0.995 和 0.85,95%CI 0.80-0.91]和呼吸窘迫综合征[RR 0.83,95%CI 0.70-0.97 和 0.78,95%CI 0.72-0.84]。然而,难民及时参加第一次常规疫苗接种的婴儿保健服务的可能性较低[RR 0.92,95%CI 0.88-0.95]。所有组的产后糖尿病发病率均较高,但难民妇女的风险增加[风险比 1.23,95%CI 1.11-1.37]。

结论

尽管导致移民的情况不同,但与其他移民相比,难民有类似的“健康移民效应”,GDM 不良结局也是如此。然而,难民新生儿接受婴儿保健服务的可能性较低,而难民妇女产后患糖尿病的风险也特别高。这些都是重要的公共卫生问题。

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