Bonne Stephanie L, Kadri Sameer S
Division of Trauma and Critical Care, Department of Surgery, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07101, USA.
Clinical Epidemiology Section, Department of Critical Care Medicine, National Institutes of Health Clinical Center, 10 Center Drive 10/2C145, Bethesda, MD 20892, USA.
Infect Dis Clin North Am. 2017 Sep;31(3):497-511. doi: 10.1016/j.idc.2017.05.011.
Despite advances in antibiotic and surgical management and supportive care for necrotizing soft tissue infections, morbidity and mortality remain substantial. Although there are clinical practice guidelines in place, there still remains much variability in choice and duration of antibiotic therapy, time to initial surgical debridement, and use of adjuvant medical therapies. This article offers an overview of necrotizing soft tissue infections with a focus on current diagnostic and treatment modalities.
尽管在坏死性软组织感染的抗生素治疗、手术处理及支持治疗方面取得了进展,但发病率和死亡率仍然很高。虽然已有临床实践指南,但在抗生素治疗的选择和疗程、首次手术清创的时机以及辅助药物治疗的使用方面仍存在很大差异。本文概述了坏死性软组织感染,重点介绍当前的诊断和治疗方式。