Single dose intra-operative antimicrobial prophylaxis during prostatectomy: gentamicin compared with cefotetan.

Two hundred consecutive patients undergoing prostatectomy were given a single dose of gentamicin or cefotetan intra-operatively. Both antibiotics afforded good protection against postoperative bacteriuria and septicaemic symptoms were fewer in those patients given cefotetan, although this difference was not statistically significant.