Pelc S, Gompel C, Simonet M L
Virchows Arch B Cell Pathol Incl Mol Pathol. 1986;51(6):487-95. doi: 10.1007/BF02899054.
Immunohistochemical evidence has recently been provided that in the normal adrenal medulla as well as in autonomic ganglia, satellite cells and Schwann cells react with S-100 protein antiserum. In the light of these data, we investigated primary peripheral neuroblastoma and ganglioneuroblastoma to determine firstly whether both cell populations actually exist in the malignancies, using the definite criteria of electron microscopy for their identification, and secondly whether they express S-100 protein using on immunohistochemical technique and light microscopy. The results indicate that in both neuroblastoma variants, satellite and Schwann cells are present and specifically express the S-100 antigen.
最近有免疫组化证据表明，在正常肾上腺髓质以及自主神经节中，卫星细胞和施万细胞与S-100蛋白抗血清发生反应。鉴于这些数据，我们研究了原发性外周神经母细胞瘤和神经节神经母细胞瘤，首先使用电子显微镜的明确标准来确定这两种细胞群体在恶性肿瘤中是否实际存在，其次使用免疫组化技术和光学显微镜来确定它们是否表达S-100蛋白。结果表明，在这两种神经母细胞瘤变体中，卫星细胞和施万细胞均存在并特异性表达S-100抗原。
