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经磁共振成像(MRI)证实为内侧半月板撕裂的中年患者报告了通常与膝关节骨关节炎相关的症状。

Middle-aged patients with an MRI-verified medial meniscal tear report symptoms commonly associated with knee osteoarthritis.

作者信息

Hare Kristoffer B, Stefan Lohmander L, Kise Nina Jullum, Risberg May Arna, Roos Ewa M

机构信息

a Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark , Denmark.

b Department of Orthopedics , Slagelse Hospital , Region Zealand , Denmark.

出版信息

Acta Orthop. 2017 Dec;88(6):664-669. doi: 10.1080/17453674.2017.1360985. Epub 2017 Aug 8.

Abstract

Background and purpose - No consensus exists on when to perform arthroscopic partial meniscectomy in patients with a degenerative meniscal tear. Since MRI and clinical tests are not accurate in detecting a symptomatic meniscal lesion, the patient's symptoms often play a large role when deciding when to perform surgery. We determined the prevalence and severity of self-reported knee symptoms in patients eligible for arthroscopic partial meniscectomy due to a degenerative meniscal tear. We investigated whether symptoms commonly considered to be related to meniscus injury were associated with early radiographic signs of knee osteoarthritis. Patients and methods - We included individual baseline items from the Knee injury and Osteoarthritis Outcome Score collected in 2 randomized controlled trials evaluating treatment for an MRI-verified degenerative medial meniscal tears in 199 patients aged 35-65 years. Each item was scored as no, mild, moderate, severe, extreme, and at least "mild" considering the symptoms present. Early radiographic signs of osteoarthritis, defined as a Kellgren and Lawrence grade of at least 1, were seen in 70 patients. Results - At least monthly knee pain, pain during stair walking and when twisting on the knee, and lack of confidence in knee was present in at least 80% of the patients. Median severity was at least moderate for knee pain, pain when twisting on the knee, pain walking on stairs, lack of confidence in knee, and clicking. Mechanical symptoms such as catching were rare. Early radiographic signs of osteoarthritis were associated with an increased risk of self-reported swelling, catching, and stiffness later in the day; the odds ratio was 2.4 (95% CI 1.2-4.9), 2.3 (1.2-4.3), and 2.3 (1.1-5.0), respectively. Interpretation - Middle-aged patients with a degenerative medial meniscus tear reported symptoms commonly associated with knee osteoarthritis. Frequent knee pain, presence of lack of confidence in the knee, and clicking did not distinguish those with a meniscal tear alone from those with early radiographic knee OA. Our findings support the notion that symptoms reported by those with a degenerative meniscal tear represent early signs of knee osteoarthritis.

摘要

背景与目的——对于何时对退行性半月板撕裂患者进行关节镜下部分半月板切除术,目前尚无共识。由于MRI和临床检查在检测有症状的半月板损伤方面并不准确,因此在决定何时进行手术时,患者的症状往往起着很大的作用。我们确定了因退行性半月板撕裂而适合进行关节镜下部分半月板切除术的患者自我报告的膝关节症状的患病率和严重程度。我们调查了通常被认为与半月板损伤相关的症状是否与膝关节骨关节炎的早期影像学表现有关。患者与方法——我们纳入了在两项随机对照试验中收集的膝关节损伤和骨关节炎疗效评分的个体基线项目,这两项试验评估了199名年龄在35至65岁之间经MRI证实的退行性内侧半月板撕裂的治疗情况。根据存在的症状,每个项目的评分分为无、轻度、中度、重度、极重度,且至少为“轻度”。70名患者出现了骨关节炎的早期影像学表现,定义为Kellgren和Lawrence分级至少为1级。结果——至少80%的患者至少每月出现膝关节疼痛、上下楼梯时疼痛以及膝盖扭转时疼痛,并且对膝盖缺乏信心。膝关节疼痛、膝盖扭转时疼痛、上下楼梯时疼痛、对膝盖缺乏信心以及弹响的严重程度中位数至少为中度。卡顿等机械性症状很少见。骨关节炎的早期影像学表现与当天晚些时候自我报告的肿胀、卡顿和僵硬风险增加相关;优势比分别为2.4(95%CI 1.2 - 4.9)、2.3(1.2 - 4.3)和2.3(1.1 - 5.0)。解读——患有退行性内侧半月板撕裂的中年患者报告了通常与膝关节骨关节炎相关的症状。频繁的膝关节疼痛、对膝盖缺乏信心以及弹响并不能区分单纯半月板撕裂患者和有膝关节骨关节炎早期影像学表现的患者。我们的研究结果支持这样一种观点,即退行性半月板撕裂患者报告的症状代表了膝关节骨关节炎的早期迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a65d/5694812/d0ff6d1331b4/iort-88-664.F01.jpg

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