用于软骨组织修复的 RGO/壳聚糖薄膜的生物相容性和制备。
Biocompatibility and fabrication of RGO/chitosan film for cartilage tissue recovery.
机构信息
Department of Trauma and Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Department of Spine Surgery, Changhai Hospital of Second Military Medical University, Shanghai, 200433, China.
出版信息
Environ Toxicol Pharmacol. 2017 Sep;54:199-203. doi: 10.1016/j.etap.2017.07.006. Epub 2017 Jul 17.
Graphene oxide (GO) has been successfully deoxygenated via an environmental friendly approach using chitosan. The prepared RGO was characterized using several microscopic and spectroscopic techniques. Also, the synthesized RGO is used to develop a highly compatible film with chitosan. Further, the in-vitro cytotoxicity results showed the biocompatible nature of prepared RGO/chitosan composite towards the human articular chondrocytes indicating their use in future cartilage tissue engineering applications.
氧化石墨烯（GO）已成功通过使用壳聚糖的环保方法脱氧。使用几种微观和光谱技术对制备的还原氧化石墨烯（RGO）进行了表征。此外，所合成的 RGO 用于开发与壳聚糖具有高相容性的薄膜。此外，体外细胞毒性结果表明，所制备的 RGO/壳聚糖复合材料对人关节软骨细胞具有生物相容性，表明它们可用于未来的软骨组织工程应用。
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