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吸烟状况对成人脊柱畸形择期脊柱融合术(≥3节段)后30天并发症和再入院率影响的降低:一项对839例患者的单机构研究

Reduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients.

作者信息

Elsamadicy Aladine A, Adogwa Owoicho, Sergesketter Amanda, Vuong Victoria D, Lydon Emily, Behrens Shay, Cheng Joseph, Bagley Carlos A, Karikari Isaac O

机构信息

Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA.

Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

World Neurosurg. 2017 Nov;107:233-238. doi: 10.1016/j.wneu.2017.07.174. Epub 2017 Aug 5.

Abstract

BACKGROUND

Smoking status has been shown to affect postoperative outcomes after surgery. The aim of this study was to determine whether patients' smoking status impacts 30-day complication and readmission rates after elective complex spinal fusion (≥3 levels).

METHODS

The medical records of 839 adult spinal deformity patients undergoing elective complex spinal fusion (≥3 levels) at a major academic institution from 2005 to 2015 were reviewed. We identified 124 (14.8%) smokers and 715 (85.2%) nonsmokers. Patient demographics, comorbidities, intraoperative and postoperative complications, and 30-day readmission rates were collected for each patient. The primary outcome investigated in this study was the rate of 30-day postoperative complication and readmission rates.

RESULTS

Patient demographics and comorbidities were similar between both groups, including age, sex, and body mass index. Median [interquartile] number of fusion levels and operative time were similar between the cohorts (smoker: 5 [4-7] vs. nonsmoker: 5 [4-8], P = 0.58) and (smoker: 309.6 ± 157.9 minutes vs. nonsmoker: 287.5 ± 131.7 minutes, P = 0.16), respectively. Both cohorts had similar postoperative complication rates and lengths of hospital stay. There was no significant difference in 30-day readmission between the cohorts (smoker: 12.9% vs. nonsmoker: 10.8%, P = 0.48). There were no observed differences in 30-day complication rates, including pain (P = 0.46), UTI (P = 0.54), hardware failure (P = 0.36), wound dehiscence (P = 0.29), and wound drainage (P = 0.86). Smokers had greater rates of 30-day cellulitis (smoker: 1.6% vs. nonsmoker: 0.3%, P = 0.05) and DVT (smoker: 0.8% vs. nonsmoker: 0.0%, P = 0.02).

CONCLUSIONS

Our study suggests that smoking does not significantly affect 30-day readmission rates after complex spinal surgery requiring ≥3 levels of fusion. Further studies are necessary to corroborate our findings.

摘要

背景

吸烟状况已被证明会影响手术后的术后结果。本研究的目的是确定患者的吸烟状况是否会影响择期复杂脊柱融合术(≥3个节段)后的30天并发症和再入院率。

方法

回顾了2005年至2015年在一家主要学术机构接受择期复杂脊柱融合术(≥3个节段)的839例成人脊柱畸形患者的病历。我们确定了124名(14.8%)吸烟者和715名(85.2%)非吸烟者。收集了每位患者的人口统计学资料、合并症、术中及术后并发症以及30天再入院率。本研究调查的主要结局是术后30天并发症发生率和再入院率。

结果

两组患者的人口统计学资料和合并症相似,包括年龄、性别和体重指数。两组患者的融合节段中位数[四分位间距]和手术时间相似(吸烟者:5[4 - 7] vs.非吸烟者:5[4 - 8],P = 0.58)以及(吸烟者:309.6±157.9分钟 vs.非吸烟者:287.5±131.7分钟,P = 0.16)。两组患者的术后并发症发生率和住院时间相似。两组患者的30天再入院率无显著差异(吸烟者:12.9% vs.非吸烟者:10.8%,P = 0.48)。在30天并发症发生率方面未观察到差异,包括疼痛(P = 0.46)、尿路感染(P = 0.54)、内固定失败(P = 0.36)、伤口裂开(P = 0.29)和伤口引流(P = 0.86)。吸烟者的30天蜂窝织炎发生率更高(吸烟者:1.6% vs.非吸烟者:0.3%,P = 0.05)和深静脉血栓形成发生率更高(吸烟者:0.8% vs.非吸烟者:0.0%,P = 0.02)。

结论

我们的研究表明,吸烟对需要≥3个节段融合的复杂脊柱手术后的30天再入院率没有显著影响。需要进一步的研究来证实我们的发现。

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