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肥胖对成人脊柱畸形矫正后路长节段融合(≥7 节段)患者短期手术结局、患者报告疼痛评分和 30 天内再入院率的影响降低。

Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction.

机构信息

Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut, USA.

Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut, USA.

出版信息

World Neurosurg. 2019 Jul;127:e108-e113. doi: 10.1016/j.wneu.2019.02.165. Epub 2019 Mar 12.

Abstract

OBJECTIVE

In the past decade, prevalence of obesity in the United States have been soaring at a disparaging rate. Previous spine studies have associated obesity with inferior surgical outcomes, increased complication and 30-day readmission rates, and worsening patient-reported outcomes. However, there is a paucity of data identifying whether the impact of obesity is sustained in patients undergoing complex deformity correction involving 7 levels or greater. The aim of this study was to determine whether obesity impacts surgical outcomes, patient-reported pain scores, and 30-day readmission rates after complex spinal fusions ≥7 levels.

METHODS

The medical records of 112 adult patients (≥18 years old) with spine deformity undergoing elective, primary complex spinal fusion (≥7 levels) for deformity correction at a major academic institution from 2010 to 2015 were reviewed. Preoperative body mass index greater than or equal to 30 kg/m was classified as obese. Patient demographics, comorbidities, and intraoperative and postoperative complication rates were collected for each patient. Inpatient patient-reported pain scores and ambulatory status also were collected. The primary outcomes of this study were surgical outcomes, patient-reported pain scores, and 30-day readmission rates.

RESULTS

Of the 112 patients, 33 (29.5%) were obese (obese: n = 33 vs. non-obese: n = 79). Patient demographics and comorbidities were similar between both cohorts, including age, sex, diabetes, hypertension, and home narcotic use. The median number of fusion levels operated, length of surgery, estimated blood loss, transfusion, and complication rates were similar between both cohorts. Moreover, the postoperative complication profiles between the cohorts also were similar, with a comparable length of hospital stay (obese: 6.5 ± 4.6 days vs. non-obese: 7.0 ± 3.9 days, P = 0.5833) and 30-day readmission rates (obese: 12.1% vs. non-obese: 13.9%, P = 0.7984). Baseline (P = 0.6826), first (P = 0.9691), and last (P = 0.9583) postoperative patient-reported pain scores were similar between cohorts. Analogously, ambulatory status was similar between the cohorts, including days from operating room to ambulation (P = 0.3471) and number of steps on first (P = 0.9173) and last (P = 0.1634) ambulatory day before discharge.

CONCLUSIONS

Our study suggests that obesity does not significantly affect surgical outcomes, patient-reported pain scores, and 30-day readmission rates after complex spinal surgery requiring ≥7 levels of fusion. Further studies are necessary to corroborate our findings.

摘要

目的

在过去的十年中,美国肥胖症的患病率以惊人的速度飙升。先前的脊柱研究表明,肥胖与手术结果不佳、并发症和 30 天再入院率增加以及患者报告的预后恶化有关。然而,关于肥胖对涉及 7 个或更多水平的复杂畸形矫正患者的影响是否持续存在的数据很少。本研究旨在确定肥胖是否会影响复杂脊柱融合术(≥7 个水平)后患者的手术结果、患者报告的疼痛评分和 30 天再入院率。

方法

回顾了 2010 年至 2015 年在一家主要学术机构接受择期、原发性复杂脊柱融合术(≥7 个水平)治疗畸形矫正的 112 例成年脊柱畸形患者(≥18 岁)的医疗记录。术前 BMI 大于或等于 30kg/m 被归类为肥胖。收集每位患者的人口统计学数据、合并症和围手术期并发症发生率。还收集了住院患者报告的疼痛评分和活动状态。本研究的主要结局是手术结果、患者报告的疼痛评分和 30 天再入院率。

结果

在 112 例患者中,有 33 例(29.5%)为肥胖(肥胖组:n=33 例;非肥胖组:n=79 例)。两组患者的人口统计学数据和合并症相似,包括年龄、性别、糖尿病、高血压和家庭麻醉药物使用情况。两组患者的融合节段数、手术时间、估计失血量、输血和并发症发生率相似。此外,两组患者的术后并发症谱也相似,住院时间相似(肥胖组:6.5±4.6 天;非肥胖组:7.0±3.9 天,P=0.5833),30 天再入院率也相似(肥胖组:12.1%;非肥胖组:13.9%,P=0.7984)。两组患者的基线(P=0.6826)、首次(P=0.9691)和末次(P=0.9583)患者报告的疼痛评分相似。同样,两组患者的活动状态也相似,包括从手术室到活动的天数(P=0.3471)和首次(P=0.9173)和末次(P=0.1634)活动日的步数。

结论

我们的研究表明,肥胖不会显著影响复杂脊柱手术后的手术结果、患者报告的疼痛评分和 30 天再入院率,这些手术需要融合≥7 个水平。需要进一步的研究来证实我们的发现。

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