Machave Y V, Dhot P S
DDMS, HQ Bengal Area (Med), Calcutta 700 021.
Associate Professor, Department of Blood Transfusion and Immunohaematology, Armed Forces Medical College, Pune 411 040.
Med J Armed Forces India. 1999 Oct;55(4):313-314. doi: 10.1016/S0377-1237(17)30357-X. Epub 2017 Jun 26.
The transfusion of blood and blood products exposes recipients to both infectious and non-infectious adverse effects. Information on HCV infection in India is still sketchy. Data on small numbers of volunteer including replacement blood donors tested by ELISA has shown rates of 0.2-4%. 6602 volunteer including replacement blood donors reported to the Department of Transfusion Medicine, Armed Forces Medical College, Pune with effect from 01 September 97 to 31 July 98. Screening for anti-HCV antibody was done by third generation ELISA kits. 29 donors were positive for anti-HCV antibody. The prevalence rate of HCV infection is 0.44% which compares with the studies from other centres. The prevalence rate was higher in the replacement donors as compared to voluntary donors. There is a need to include anti-HCV to the list of mandatory tests for screening of blood donors.
输血及血液制品的输注会使受血者面临感染性和非感染性不良反应。印度关于丙肝病毒（HCV）感染的信息仍然不完整。对包括替代献血者在内的少量志愿者进行酶联免疫吸附测定（ELISA）检测的数据显示，感染率为0.2% - 4%。自1997年9月1日至1998年7月31日，有6602名包括替代献血者在内的志愿者向浦那武装部队医学院输血医学系报告情况。使用第三代ELISA试剂盒进行抗HCV抗体筛查。29名献血者抗HCV抗体呈阳性。HCV感染的患病率为0.44%，与其他中心的研究结果相当。替代献血者中的患病率高于自愿献血者。有必要将抗HCV纳入献血者筛查的强制检测项目清单。
