Lin Chia-Hua, Chen Hsiang-Cheng, Gao Hong-Wei, Wu Bai-Yao
Department of Dermatology, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan.
Division of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan.
Australas J Dermatol. 2018 May;59(2):e135-e137. doi: 10.1111/ajd.12698. Epub 2017 Aug 9.
Immediate and delayed hypersensitivity reactions may occur after the first or many exposures to tocilizumab, and they have varying presentations. Here, we describe a Wolf's isotopic response that manifested in a patient as erythema on the same site of a previous healed herpes zoster infection. This phenomenon has rarely been reported in the literature.
首次或多次接触托珠单抗后可能会发生速发型和迟发型超敏反应,且表现各异。在此,我们描述了一例在一名患者身上出现的沃尔夫同形反应,表现为在先前愈合的带状疱疹感染部位出现红斑。这种现象在文献中鲜有报道。