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印度冠心病患者评估与管理调查(SMART)

Survey of Assessment and MAnagement of CoRonary Heart Disease PaTients (SMART) in India.

作者信息

Singh Amit, Singh Vikram, Ranjan Rupesh

机构信息

Ex- MSD Pharmaceuticals Pvt. Ltd.

Medical Affairs, MSD Pharmaceuticals Pvt. Ltd., Mumbai, Maharashtra.

出版信息

J Assoc Physicians India. 2017 Jul;65(7):22-26.

Abstract

OBJECTIVE

Survey of Assessment and MAnagement of CoRonary Heart Disease PaTients was undertaken to describe profile and management pattern of adult Acute Coronary Syndrome (ACS) patients from presentation till discharge, in private tertiary care Indian hospitals.

MATERIALS AND METHODS

This was an observational, prospective study. Based on standard criteria, patients were diagnosed to have ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI) or unstable angina (UA). For patients surviving till hospital discharge, demographic characteristics, medical history, time to hospital presentation, investigations, vascular interventions and medical management during the hospital stay were recorded.

RESULTS

In total, 1340 patients with definitive ACS diagnosis and surviving their hospital stay were enrolled. Mean patient age was 58.7 years, 75% were males and 36.9% were diagnosed with STEMI, 8.9% with NSTEMI and 54.2% with UA. 41.9%, 35% and 18.4% patients reached hospital within 6 hours for STEMI, NSTEMI and UA respectively. Pre-existing hypertension and diabetes were observed less frequently in patients with STEMI (54.8%, 31.9%) than in NSTEMI (70.8%, 45.8%) or UA (64.2%, 41.5%). Aspirin, clopidogrel, nitrates, β-Blockers, angiotensin converting enzyme inhibitors and statins were used more frequently in NSTEMI than in STEMI or UA patients. Percutaneous trans-coronary angioplasty was performed more commonly in STEMI (64.2%) than in NSTEMI (41.7%) or UA (41.2%).

CONCLUSIONS

UA is the commonest and NSTEMI is the least common type of ACS observed in our study. We observed important differences in patient profile, time to hospital presentation, in-hospital acute pharmacological management and vascular interventions performed between the three different types of ACS.

摘要

目的

开展冠心病患者评估与管理调查,以描述印度私立三级医疗医院中成年急性冠状动脉综合征(ACS)患者从就诊到出院的概况及管理模式。

材料与方法

这是一项观察性前瞻性研究。根据标准标准,患者被诊断为ST段抬高型心肌梗死(STEMI)、非ST段抬高型心肌梗死(NSTEMI)或不稳定型心绞痛(UA)。对于存活至出院的患者,记录其人口统计学特征、病史、就诊时间、检查、血管介入治疗及住院期间的药物治疗情况。

结果

共纳入1340例确诊为ACS且存活至出院的患者。患者平均年龄为58.7岁,75%为男性,36.9%被诊断为STEMI,8.9%为NSTEMI,54.2%为UA。STEMI、NSTEMI和UA患者分别有41.9%、35%和18.4%在6小时内到达医院。STEMI患者(54.8%,31.9%)中既往高血压和糖尿病的发生率低于NSTEMI患者(70.8%,45.8%)或UA患者(64.2%,41.5%)。NSTEMI患者使用阿司匹林、氯吡格雷、硝酸盐、β受体阻滞剂、血管紧张素转换酶抑制剂和他汀类药物的频率高于STEMI或UA患者。经皮冠状动脉腔内血管成形术在STEMI患者中(64.2%)比在NSTEMI患者中(41.7%)或UA患者中(41.2%)更常见。

结论

在我们的研究中,UA是最常见的ACS类型,NSTEMI是最不常见的类型。我们观察到三种不同类型的ACS在患者概况、就诊时间、住院急性药物治疗和血管介入治疗方面存在重要差异。

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