Yeamans Carmen L, Gutierrez-Quintana Rodrigo, Haley Allison, Lamm Catherine G
From the University of Glasgow, Glasgow, United Kingdom (C.L.Y., R.G-Q.); Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia (A.H.); and Idexx Labratories, Sacramento, California (C.G.L.).
J Am Anim Hosp Assoc. 2017 Sep/Oct;53(5):265-269. doi: 10.5326/JAAHA-MS-6479. Epub 2017 Aug 9.
A 5 yr old castrated male whippet presented with a unique presentation of ambulatory paraparesis and subsequent diagnosis of primary intracranial choroid plexus carcinoma, with metastases to the cervical, thoracic, lumbar, and sacral spinal cord segments. Magnetic resonance imaging was performed initially of the thoracolumbar vertebral column and was followed by MRI sequences of the brain for confirmation of the presence of a primary intracranial tumor. The dog was euthanized immediately following diagnostic imaging due to the severity of clinical signs and poor prognosis. Postmortem examination confirmed the presence of a primary choroid plexus carcinoma, with diffuse metastatic lesions to the spinal cord. To the authors' knowledge, this is the first description of MRI findings of spinal cord metastasis of a choroid plexus carcinoma in a dog. Additionally, this case demonstrates primary clinical signs arising from metastatic lesions. This confirms the importance of extensive neuroimaging investigations when suspecting choroid plexus tumors and evaluating response to treatment regimens.
一只5岁去势雄性惠比特犬出现了非卧床性轻截瘫的独特表现，随后被诊断为原发性颅内脉络丛癌，并转移至颈、胸、腰和骶段脊髓。最初对胸腰椎进行了磁共振成像，随后对脑部进行了MRI序列检查以确认原发性颅内肿瘤的存在。由于临床症状严重且预后不良，该犬在诊断性成像后立即实施安乐死。尸检证实存在原发性脉络丛癌，并伴有脊髓弥漫性转移病变。据作者所知，这是首次对犬脉络丛癌脊髓转移的MRI表现进行描述。此外，该病例展示了由转移病变引起的主要临床症状。这证实了在怀疑脉络丛肿瘤并评估治疗方案反应时进行广泛神经影像学检查的重要性。
