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犬脊髓中疑似原发性多形性胶质母细胞瘤

Suspected primary glioblastoma multiforme in the canine spinal cord.

作者信息

Röthlisberger A, Lehmbecker A, Beineke A, Mischke R, Dziallas P, Meyer-Lindenberg A, Tipold A

机构信息

Department of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany.

出版信息

J Small Anim Pract. 2012 Oct;53(10):604-7. doi: 10.1111/j.1748-5827.2012.01263.x. Epub 2012 Aug 8.

Abstract

An eight-year-old mixed-breed dog was presented with progressive paraparesis. Neurological examination revealed a painful diffuse lesion between spinal cord segments T3 and L3. Magnetic resonance images displayed multi-focal contrast enhancing spinal cord and meningeal lesions. Cytology of these lesions revealed a malignant tumour prompting euthanasia of the dog. Histopathology confirmed the cytological diagnosis and a final diagnosis of a glioblastoma multiforme was made based on immunohistochemistry.

摘要

一只八岁的混种犬出现进行性轻截瘫。神经学检查发现脊髓T3至L3节段之间有一个疼痛性弥漫性病变。磁共振成像显示脊髓和脑膜有多处对比增强病变。这些病变的细胞学检查显示为恶性肿瘤,促使对该犬实施安乐死。组织病理学证实了细胞学诊断,并基于免疫组织化学最终诊断为多形性胶质母细胞瘤。

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