Meya U, Renfordt E
Pharmacopsychiatry. 1986 Nov;19(6):429-33. doi: 10.1055/s-2007-1017282.
The proportion of interview time spent in eye-contacts was studied before the onset of and during neuroleptic treatment in a group of 24 male schizophrenic patients. A significant increase in eye-contacts after 14 days distinguished responders to neuroleptic treatment, while a tendency towards the same effect distinguished patients treated with haloperidol from those treated with perazine. Only in the subgroup of responders was there a significant relationship between increase in eye-contacts and reduction of psychopathologic symptoms, regardless of whether these values were compared for the same treatment days or whether early changes in eye-contacts were compared with final outcome of treatment after 28 days. Since the patient subgroups were rather small, the results should still be considered preliminary. A prospective study including more parameters of visual interaction, a larger patient sample, and a longer observation period is required.
对一组24名男性精神分裂症患者在使用抗精神病药物治疗前和治疗期间，研究了访谈中目光接触所占用的时间比例。治疗14天后目光接触显著增加可区分出对抗精神病药物治疗有反应者，而同样的趋势可区分接受氟哌啶醇治疗的患者与接受奋乃静治疗的患者。仅在有反应的亚组中，目光接触增加与精神病理症状减轻之间存在显著关系，无论这些值是在相同治疗天数进行比较，还是将目光接触的早期变化与28天后的治疗最终结果进行比较。由于患者亚组相对较小，结果仍应视为初步的。需要进行一项前瞻性研究，纳入更多视觉互动参数、更大的患者样本和更长的观察期。
