Chang Ming, Chang Ming-Yi, Lin Wei-Siou, Gabayno Jacque Lynn
College of Mechanical Engineering and Automation, Huaqiao University, Xiamen 361021, Fujian, China.
Department of Mechanical Engineering, Chung Yuan Christian University, Chungli, Taoyuan 32023, Taiwan.
Materials (Basel). 2015 Nov 19;8(11):7813-7820. doi: 10.3390/ma8115429.
In this study, surface modification of iron (II, III) oxide Fe₃O₄ nanoparticles by oleic acid (OA) coating is investigated for the microablation of fat in a microchannel. The nanoparticles are synthesized by the co-precipitation method and then dispersed in organic solvent prior to mixing with the OA. The magnetization, agglomeration, and particle size distribution properties of the OA-coated Fe₃O₄ nanoparticles are characterized. The surface modification of the Fe₃O₄ nanoparticles reveals that upon injection into a microchannel, the lipophilicity of the OA coating influences the movement of the nanoparticles across an oil-phase barrier. The motion of the nanoparticles is controlled using an AC magnetic field to induce magnetic torque and a static gradient field to control linear translation. The fat microablation process in a microchannel is demonstrated using an oscillating driving field of less than 1200 Am.
在本研究中，对通过油酸（OA）包覆对氧化亚铁（II, III）Fe₃O₄纳米颗粒进行表面改性，以用于微通道中脂肪的微消融展开了研究。纳米颗粒通过共沉淀法合成，然后在与OA混合之前分散于有机溶剂中。对OA包覆的Fe₃O₄纳米颗粒的磁化、团聚和粒径分布特性进行了表征。Fe₃O₄纳米颗粒的表面改性表明，注入微通道后，OA包覆的亲脂性会影响纳米颗粒穿过油相屏障的运动。利用交流磁场诱导磁转矩以及静态梯度场控制线性平移来控制纳米颗粒的运动。使用小于1200 Am的振荡驱动场展示了微通道中的脂肪微消融过程。
