Verma Alka, Tewari Saipriya, Kannaujia Ashish
Department of Anaesthesia, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Indian J Anaesth. 2017 Jul;61(7):590-593. doi: 10.4103/ija.IJA_57_17.
Oncogenic osteomalacia (OOM) is a rare paraneoplastic syndrome associated with mesenchymal tumours. It is characterised by phosphaturia, hypophosphataemia, decreased serum Vitamin D3 levels and severe osteomalacia. OOM-inducing tumours are usually benign, arising either from bone or soft tissue, with extremities and craniofacial region being the most common sites. Surgical resection of the tumour remains the mainstay of treatment. Challenges to an anaesthesiologist arise when such patients are planned for surgical resection of the underlying tumour. All the perioperative dilemmas are directly related to the severe hypophosphataemia. We describe three such cases of OOM and their perioperative management.
致癌性骨软化症（OOM）是一种与间充质肿瘤相关的罕见副肿瘤综合征。其特征为磷酸盐尿、低磷血症、血清维生素D3水平降低以及严重的骨软化症。引发OOM的肿瘤通常为良性，起源于骨骼或软组织，四肢和颅面部区域是最常见的部位。肿瘤的手术切除仍然是主要的治疗方法。当计划对这类患者进行潜在肿瘤的手术切除时，麻醉医生会面临挑战。所有围手术期的困境都直接与严重的低磷血症有关。我们描述了三例这样的OOM病例及其围手术期管理。
