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尿动力学研究对于评估绝经后女性患者的下尿路症状是否必要?一项前瞻性观察性研究的结果。

Is urodynamic study is a necessity for evaluation of lower urinary tract symptoms in postmenopausal female patients? Result of a prospective observational study.

作者信息

Choudhury Sunirmal, Das Susanta Kumar, Jana Debarshi, Pal Dilip Kumar

机构信息

Department of Urology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.

出版信息

Urol Ann. 2017 Jul-Sep;9(3):239-243. doi: 10.4103/UA.UA_170_16.

DOI:10.4103/UA.UA_170_16
PMID:28794589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5532890/
Abstract

AIM

The aim of this study is to evaluate the causes of lower urinary tract symptoms (LUTS) in postmenopausal female patients (PMFP) and correlate their symptoms with their urodynamic study (UDS) findings.

MATERIALS AND METHODS

A prospective observational study analyzing the clinical and UDS findings of PMFP presenting with LUTS. A detailed history including history of diabetes, neurological disease, drug history, and pelvic surgeries was taken, followed by physical examination and urodynamic assessment.

RESULTS

A total of 100 patients were classified according to their predominant symptoms into three categories: (1) voiding dysfunction (45 patients), (2) storage symptoms (30 patients), and (3) urinary incontinence (25 patients). The patients with voiding LUTS could be categorized urodynamically into three grades of bladder outlet obstruction (BOO): (a) early (37.8%) (maximal flow [Qmax] >15 mL/s and detrusor pressure at maximal flow [PdetQmax] >30 cm of water), (b) compensated (31.1%) (Qmax <15 mL/s and PdetQmax >30 cm of water), and (c) late (31.1%) (Qmax <15 mL/s and PdetQmax <30 cm of water). The patients with storage symptoms could be categorized into two with either the presence of demonstrable idiopathic detrusor contractions (53.3%) or not (46.7%). The patients with incontinence were of three types: (a) stress incontinence (44%), (b) urge incontinence (28%), and (c) mixed incontinence (28%). UDS showed no demonstrable leak in nine patients (36%) and the rest had UDS findings corroborative to their symptoms.

CONCLUSIONS

Thus, the major LUTS in PMFP were BOO, storage symptoms, and incontinence. Proper evaluation of LUTS necessitates UDS and along with good physical examination can help us in reaching a correct diagnosis and plan respective treatment.

摘要

目的

本研究旨在评估绝经后女性患者(PMFP)下尿路症状(LUTS)的病因,并将其症状与尿动力学研究(UDS)结果相关联。

材料与方法

一项前瞻性观察性研究,分析出现LUTS的PMFP的临床和UDS结果。记录详细病史,包括糖尿病史、神经疾病史、用药史和盆腔手术史,随后进行体格检查和尿动力学评估。

结果

共100例患者根据其主要症状分为三类:(1)排尿功能障碍(45例),(2)储尿症状(30例),(3)尿失禁(25例)。有排尿LUTS的患者在尿动力学上可分为三个膀胱出口梗阻(BOO)等级:(a)早期(37.8%)(最大尿流率[Qmax]>15 mL/s且最大尿流率时逼尿肌压力[PdetQmax]>30 cm水柱),(b)代偿期(31.1%)(Qmax<15 mL/s且PdetQmax>30 cm水柱),(c)晚期(31.1%)(Qmax<15 mL/s且PdetQmax<30 cm水柱)。有储尿症状的患者可分为两类,一类存在明显的特发性逼尿肌收缩(53.3%),另一类不存在(46.7%)。尿失禁患者有三种类型:(a)压力性尿失禁(44%),(b)急迫性尿失禁(28%),(c)混合性尿失禁(28%)。UDS显示9例患者(36%)无明显漏尿,其余患者的UDS结果与其症状相符。

结论

因此,PMFP的主要LUTS为BOO、储尿症状和尿失禁。对LUTS进行恰当评估需要UDS,并且结合良好的体格检查有助于我们做出正确诊断并制定相应的治疗方案。

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