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隐睾症:自1960年以来明显大幅增加。约翰·拉德克利夫医院隐睾症研究小组。

Cryptorchidism: an apparent substantial increase since 1960. John Radcliffe Hospital Cryptorchidism Study Group.

出版信息

Br Med J (Clin Res Ed). 1986 Nov 29;293(6559):1401-4. doi: 10.1136/bmj.293.6559.1401.

DOI:10.1136/bmj.293.6559.1401
PMID:2879598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1342170/
Abstract

A total of 1849 boys born to mothers resident in a defined area around Oxford were examined for cryptorchidism. Those born in hospital were examined at birth and again after three months if cryptorchid at the earlier examination. The incidence of cryptorchidism at three months adjusted to the birthweight distribution of England and Wales was 1.58%. By comparison, in a very similar study conducted around 1960 the incidence was 0.96%. Hence the cryptorchidism rate had apparently increased by 65% over the two decades, which contrasted with the twofold increase in the national orchidopexy rate. The proportion of boys undergoing orchidopexy appeared consistently to be roughly twice the proportion of boys with an undescended testis at 3 months of age. The increase in cryptorchidism and disparity with the rate of orchidopexy are not easily explained and are the subjects of continuing study.

摘要

对居住在牛津周边特定区域的母亲所生的1849名男婴进行了隐睾症检查。在医院出生的婴儿在出生时接受检查,如果在早期检查时为隐睾,则在三个月后再次检查。根据英格兰和威尔士的出生体重分布调整后,三个月时隐睾症的发病率为1.58%。相比之下,在1960年左右进行的一项非常类似的研究中,发病率为0.96%。因此,在这二十年中,隐睾症发病率显然上升了65%,这与全国睾丸固定术率增加两倍形成对比。在3个月大时接受睾丸固定术的男孩比例似乎一直大致是睾丸未降男孩比例的两倍。隐睾症的增加以及与睾丸固定术率的差异难以解释,仍是持续研究的课题。

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1
Cryptorchidism: an apparent substantial increase since 1960. John Radcliffe Hospital Cryptorchidism Study Group.隐睾症:自1960年以来明显大幅增加。约翰·拉德克利夫医院隐睾症研究小组。
Br Med J (Clin Res Ed). 1986 Nov 29;293(6559):1401-4. doi: 10.1136/bmj.293.6559.1401.
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The epidemiology of cryptorchidism. John Radcliffe Hospital Cryptorchidism Research Group.隐睾症的流行病学。约翰·拉德克利夫医院隐睾症研究小组。
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本文引用的文献

1
THE DESCENT OF THE TESTIS.睾丸的下降
Arch Dis Child. 1964 Dec;39(208):605-9. doi: 10.1136/adc.39.208.605.
2
Maternal and gestational factors affecting the risk of cryptorchidism and inguinal hernia.
Int J Epidemiol. 1984 Sep;13(3):311-8. doi: 10.1093/ije/13.3.311.
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Apparent doubling of frequency of undescended testis in England and Wales in 1962-81.1962年至1981年间,英格兰和威尔士隐睾症发病率明显翻倍。
Lancet. 1984 Aug 11;2(8398):330-2. doi: 10.1016/s0140-6736(84)92697-7.
4
Undescended testis: the effect of treatment on subsequent risk of subfertility and malignancy.隐睾症:治疗对后续生育力低下和恶性肿瘤风险的影响。
J Pediatr Surg. 1986 Aug;21(8):691-6. doi: 10.1016/s0022-3468(86)80389-x.