枕部毛发强度作为侵入性毛发导致藏毛窦疾病的一种解释

Strength of Occipital Hair as an Explanation for Pilonidal Sinus Disease Caused by Intruding Hair.

作者信息

Doll Dietrich, Bosche Friederike D, Stauffer Verena K, Sinicina Inga, Hoffmann Sebastian, van der Zypen Dominic, Luedi Markus M

机构信息

1 Department of Procto-Surgery, St. Marienhospital Vechta, Academic Teaching Hospital of the Medizinische Hochschule Hannover, Vechta, Germany 2 Department of Surgery, Luzerner Kantonsspital Sursee, Sursee, Switzerland 3 Institute of Forensic Medicine, Technical University Munich, Munich, Germany 4 Marien-Krankenhaus Bergisch Gladbach, Bergisch Gladbach, Germany 5 Swiss Federal Office of Social Insurance, Bern, Switzerland 6 Department of Anesthesiology and Pain Therapy, Bern University Hospital Inselspital, University of Bern, Bern, Switzerland 7 Department of Surgery, Medical School, University of the Witwatersrand, Johannesburg, Soweto, South Africa.

出版信息

Dis Colon Rectum. 2017 Sep;60(9):979-986. doi: 10.1097/DCR.0000000000000795.

DOI:10.1097/DCR.0000000000000795

PMID:28796737

Abstract

BACKGROUND

Pilonidal sinus disease is thought to be caused by intrusion of hair into healthy skin; loose hair in the intergluteal fold is thought to promote disease. However, compelling evidence to support these postulates is lacking; the cause of pilonidal sinus disease remains uncertain.

OBJECTIVE

To determine whether particular properties of hair are associated with susceptibility to pilonidal sinus disease, we compared physical properties of hairs of patients with pilonidal sinus disease with hairs from control subjects who were matched for sex, BMI, and age.

DESIGN

This was an experimental study with establishment of a mechanical strength test for single hairs to quantify the maximum vertical force that a hair could exert, following tests of strength of occipital, lumbar, and intergluteal hair.

SETTINGS

Hair from patients with pilonidal sinus disease and matched control subjects were harvested from patients of the St. Marienhospital Vechta Department of Procto-Surgery.

PATIENTS

A total of 17 adult patients with pilonidal sinus disease and 217 control subjects were included.

MAIN OUTCOME MEASURES

ANOVA and intraclass and interclass variations of data gained from mechanical strength tests of occipital, lumbar, and intergluteal hair were included.

RESULTS

Vertical hair strength was significantly greater in patients with pilonidal sinus disease. Occipital hair exhibited 20% greater, glabella sacralis 1.1 times greater, and intergluteal hair 2 times greater strength in patients with pilonidal sinus disease than in matched control subjects (all p = 0.0001). In addition, patients with pilonidal sinus disease presented with significantly more hair at the glabella sacralis and in the intergluteal fold.

LIMITATIONS

The study was limited by its relatively small number of patients from a specific cohort of European patients.

CONCLUSIONS

Occipital hair exhibited considerable vertical strength. Because occipital hair exerted the greatest force and cut hair fragments were found in the pilonidal nest in large quantities, these data suggest that pilonidal sinus disease is promoted by occipital hair. See Video Abstract at http://links.lww.com/DCR/A435.

摘要